Evidence map›Paper›PMID 39495143›Full record

ArticleJNCI cancer spectrum2024

County-level racial disparities in prostate cancer-specific mortality from 2005 to 2020.

Samuel L Washington Iii, Mary Fakunle, Lufan Wang, Avery E Braun, Michael Leapman, Janet E Cowan, Matthew R Cooperberg

Abstract read
In one paragraph

Article in JNCI cancer spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Samuel L Washington IiiDepartment of Urology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94143, United States.ORCID 0000-0002-2467-6115
Mary FakunleDepartment of Urology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94143, United States.ORCID 0009-0008-5785-4126
Lufan WangDepartment of Urology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94143, United States.
Avery E BraunDepartment of Urology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94143, United States.
Michael LeapmanDepartment of Urology, Yale University, New Haven, CT 06510, United States.ORCID 0000-0002-0727-7614
Janet E CowanDepartment of Urology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94143, United States.
Matthew R CooperbergDepartment of Urology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94143, United States.ORCID 0000-0003-4339-6685

Funding

Cancer Translational BiologyGoldberg-Benioff Endowed Professorship in Cancer Biology
6 · The paper itself

Abstract

backgroundLocal conditions where people live continue to influence prostate cancer outcomes. By examining local characteristics associated with trends in Black-White differences in prostate cancer-specific mortality over time, we aim to identify factors driving county-level prostate cancer-specific mortality disparities over a 15-year period.

methodsWe linked county-level data (Area Health Resource File) with clinicodemographic data of men with prostate cancer (Surveillance, Epidemiology, and End Results registry) from 2005 to 2020. Generalized linear mixed models evaluated associations between race and county-level age-standardized prostate cancer-specific mortality, adjusting for age; year of death; rurality; county-level education; income; uninsured rates; and densities of urologists, radiologists, primary care practitioners, and hospital beds.

resultsIn 1085 counties, 185 390 patients were identified of which 15.8% were non-Hispanic Black. Racial disparities in prostate cancer-specific mortality narrowed from 2005 to 2020 (25.4 per 100 000 to 19.2 per 100 000 overall, 57.9 per 100 000 to 38 per 100 000 for non-Hispanic Black patients, and 23.4 per 100 000 to 18.3 per 100 000 for non-Hispanic White patients). For non-Hispanic Black and non-Hispanic White patients, county prostate cancer-specific mortality changes varied greatly (-65% to +77% and -61% to +112%, respectively). From 2016 to 2020, non-Hispanic Black patients harbored greater prostate cancer-specific mortality risk (relative risk = 2.09, 95% confidence interval [CI] = 2.01 to 2.18); higher radiation oncologist density was associated with lower mortality risk (relative risk = 0.93, 95% CI = 0.89 to 0.98), while other practitioner densities were not.

conclusionAlthough overall rates improved, specific counties experienced worsening race-based disparities over time. Identifying locations of highest (and lowest) mortality disparities remains critical to development of location-specific solutions to racial disparities in prostate cancer outcomes.

Indexed as

Black or African AmericanHealth Status DisparitiesProstatic NeoplasmsSEER ProgramAgedEducational StatusHumansIncomeLinear ModelsMaleMedically UninsuredMiddle AgedRural PopulationUnited StatesWhite

Identifiers

PMID39495143
PMCPMC11631307

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.