ReviewHaemophilia : the official journal of the World Federation of Hemophilia2024
The haemophilia joint health score for the assessment of joint health in patients with haemophilia.
Review in Haemophilia : the official journal of the World Federation of Hemophilia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Dose or Timing? The Role of Prophylaxis in Preventing Joint Bleeds in Hemophilia: A Cross-Generational Comparative Analysis.The Eurasian journal of medicine · 2026Article
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- Article
- Genotype-Specific Postural Control Deficits in Hemophilia A: Insights from Center of Pressure Analysis Beyond Radiographic Arthropathy.International journal of molecular sciences · 2026Article
- Persons with high Hemophilia Joint Health Scores have reduced functional range of motion during simulated sports activities.Research and practice in thrombosis and haemostasis · 2026Article
- The Psychometric Properties of the Moberg Pick-Up Test (MPUT) to Assess Fine Motor Skills in Adults with Haemophilia.Healthcare (Basel, Switzerland) · 2026Article
- Joint tissue plasticity in hemophilia: insights from the Joint Activity and Damage Exam ultrasound protocol.Research and practice in thrombosis and haemostasis · 2026Article
- AOZORA study: 3-year interim analysis of safety and joint health in pediatric people with hemophilia A receiving emicizumab prophylaxis.Research and practice in thrombosis and haemostasis · 2025Article
- Efficacy and Safety of Manual Therapy in Haemophilic Ankle Arthropathy: A Randomised Crossover Clinical Trial.Healthcare (Basel, Switzerland) · 2025Article
- Joint health status in people with moderate hemophilia A: a cross-sectional multicenter study.Research and practice in thrombosis and haemostasis · 2025Article
- An assessment of burden associated with problem joints in children and adults with moderate or severe haemophilia A: analysis of the CHESS-Paediatrics and CHESS II cross-sectional studies.Orphanet journal of rare diseases · 2025Article
- The haemophilia joint health score for the assessment of joint health in patients with haemophilia.Haemophilia : the official journal of the World Federation of Hemophilia · 2024Review
- Haemophilia Joint Health Score Ranges Across the Lifespan: Variation by Haemophilia Type and Severity.Haemophilia : the official journal of the World Federation of HemophiliaArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
introductionThe haemophilia joint health score (HJHS) is a tool used to assess joint changes in patients with haemophilia. There is lack of consensus on the interpretation of HJHS scores and their clinical relevance.
aimTo evaluate available literature reporting HJHS changes over time and assess a possible cut-off value for clinically relevant outcomes and the ideal follow-up for a meaningful score change.
methodsWe conducted a literature search of studies published between 2011 and 2023 where the HJHS version 2.1 had been adopted to detect changes in joint health in patients with haemophilia. We focused on studies that assessed clinical relevance of HJHS changes, evaluated the use of cut-off values and reported a follow-up over time.
resultsOur search identified 213 publications of which 53 (25%) were deemed relevant for this review. Of these, 33 (62%) publications reported the total HJHS score and 20 (38%) reported a single joint HJHS score, while the way of reporting HJHS scores/change was highly variable. Ten publications (19%) assessed clinical relevance, but their methods of calculation differed (defining a cut-off score, measuring standardised response mean or minimal detectable change). The follow-up duration varied from 2 weeks to 8 years in these 10 studies.
conclusionsHigh variability in assessing HJHS change over time is the primary consequence of its low sensitivity, and the lack of consensus on interpretation and clinical relevance of the score. Therefore, more sensitive tools should be used alongside HJHS to better define the joint health status of patients with haemophilia.
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