Evidence map›Paper›PMID 39494875›Full record

ArticleInfection and immunity2024

Establishment of CD1b-restricted immunity to lipid antigens in the pulmonary response to

Macallister C Harris, Hadley E Gary, Sarah K Cooper, David F Ackart, James E DiLisio, Randall J Basaraba, Tan-Yun Cheng, Ildiko van Rhijn, D Branch Moody, Brendan K Podell

Abstract read
In one paragraph

Article in Infection and immunity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. CD8+ lymphocytes in immunity against tuberculosis.Journal of immunology (Baltimore, Md. : 1950) · 2026
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Macallister C HarrisMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Hadley E GaryMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Sarah K CooperMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
David F AckartMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
James E DiLisioMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Randall J BasarabaMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Tan-Yun ChengBrigham and Women's Hospital, Division of Rheumatology, Inflammation and Immunity, Harvard Medical School, Boston, Massachusetts, USA.
Ildiko van RhijnBrigham and Women's Hospital, Division of Rheumatology, Inflammation and Immunity, Harvard Medical School, Boston, Massachusetts, USA.
D Branch MoodyBrigham and Women's Hospital, Division of Rheumatology, Inflammation and Immunity, Harvard Medical School, Boston, Massachusetts, USA.
Brendan K PodellMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.ORCID 0000-0003-2548-8826

Funding

Metabolomics Core U19AI111224 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI MOODY, DAVID BRANCH, MURRAY, MEGAN B · 2015 to 2021
$20.4M
T cell response to CDI-restricted lipids in tuberculosisR01AI049313 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI MOODY, DAVID BRANCH · 2001 to 2025
$10.6M
Biomedical Research Training for VeterinariansT32OD010437 · OD · COLORADO STATE UNIVERSITY · PI Gregg A Dean, KELLY S SANTANGELO · 2012 to 2026
$6.2M
NRSA Training CoreTL1TR002533 · NCATS · UNIVERSITY OF COLORADO DENVER · PI CICUTTO, LISA · 2018 to 2022
$3.0M
CSU Infectious Disease Research and Response Training ProgramT32AI162691 · NIAID · COLORADO STATE UNIVERSITY · PI DEAN, GREGG A · 2021 to 2025
$2.1M
Mechanisms of Diabetic Susceptibility to TuberculosisK01OD016997 · OD · COLORADO STATE UNIVERSITY · PI PODELL, BRENDAN · 2014 to 2018
$615k
Vectra Polaris microscope imaging systemS10OD030263 · OD · COLORADO STATE UNIVERSITY · PI GONZALEZ-JUARRERO, MERCEDES · 2021 to 2021
$452k
HHS | NIH | National Center for Advancing Translational Sciences (NCATS) TL1TR002533HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) 3R01AI049313HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) U19AI111224HHS | NIH | NIH Office of the Director (OD) 5T32OD010437-19HHS | NIH | NIH Office of the Director (OD) K01OD016997NCATS NIH HHS TL1 TR002533NIAID NIH HHS R01 AI049313NIAID NIH HHS T32 AI162691NIAID NIH HHS U19 AI111224NIH HHS K01 OD016997NIH HHS S10 OD030263NIH HHS T32 OD010437NSF | Office of the Director (OD) 1310OD030263
6 · The paper itself

Abstract

CD1 is an antigen-presenting glycoprotein homologous to MHC I; however, CD1 proteins present lipid rather than peptide antigens. CD1 proteins are well established to present lipid antigens of

Indexed as

Antigens, BacterialAntigens, CD1LungMycobacterium tuberculosisAnimalsB-LymphocytesDisease Models, AnimalFemaleGuinea PigsLipidsTuberculosisTuberculosis, PulmonaryAntigens, BacterialAntigens, CD1CD1b antigenLipidsCD1CD1bguinea piglipid antigenMycobacteriumpulmonary immunitytuberculosis

Identifiers

PMID39494875
PMCPMC11629625

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.