Evidence map›Paper›PMID 39494472›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

PD-1

Jie Long, Si-Yu Yang, Zhen-Hua Bian, Hao-Xian Zhu, Min Ma, Xiao-Qing Wang, Liang Li, Weici Zhang, Ying Han, M Eric Gershwin and 2 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. [The role of hepatocyte programmed cell death in liver fibrosis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026
    Review
  2. Experimental Models of Autoimmune Hepatitis: Disease Fidelity and Translational Relevance.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. PD-1Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jie LongMedical Research Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China.
Si-Yu YangGuangdong Cardiovascular Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China.
Zhen-Hua BianSchool of Biomedical Sciences and Engineering, South China University of Technology, Guangzhou International Campus, Guangzhou, 511442, China.
Hao-Xian ZhuSchool of Medicine, South China University of Technology, Guangzhou, 510006, China.
Min MaSchool of Medicine, South China University of Technology, Guangzhou, 510006, China.
Xiao-Qing WangSchool of Medicine, South China University of Technology, Guangzhou, 510006, China.
Liang LiMedical Research Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China.
Weici ZhangDivision of Rheumatology, Allergy and Clinical Immunology, University of California Davis, Davis, CA, 95616, USA.
Ying HanState Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Air Force Military Medical University, Xi'an, 710000, China.
M Eric GershwinDivision of Rheumatology, Allergy and Clinical Immunology, University of California Davis, Davis, CA, 95616, USA.
Zhe-Xiong LianGuangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China.ORCID 0000-0002-9525-1421
Zhi-Bin ZhaoMedical Research Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China.

Funding

National Natural Science Foundation of China 32100720National Natural Science Foundation of China 81820108005National Natural Science Foundation of China 82120108013National Natural Science Foundation of China 82370528
6 · The paper itself

Abstract

The specific mechanisms underlying effector pathways in autoimmune liver disease remain enigmatic and therefore constructing appropriate murine models to investigate disease pathogenesis becomes critical. A spontaneous severe murine model of autoimmune liver disease has been previously established in dnTGFβRII Aire

Indexed as

CD8-Positive T-LymphocytesDisease Models, AnimalDisease ProgressionHepatocytesProgrammed Cell Death 1 ReceptorPyroptosisAnimalsAutoimmune DiseasesHepatitis, AutoimmuneMiceMice, Inbred C57BLPdcd1 protein, mouseProgrammed Cell Death 1 Receptoraireautoimmune liver diseasednTGFβRIIPD‐1+CD8+ T cellspyroptosis

Identifiers

PMID39494472
PMCPMC11714232

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.