ArticleTransplant international : official journal of the European Society for Organ Transplantation2024
Promising Results of Kidney Transplantation From Donors Following Euthanasia During 10-Year Follow-Up: A Nationwide Cohort Study.
Article in Transplant international : official journal of the European Society for Organ Transplantation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Organ donation and brain preservation after assisted dying: case report and considerations for a potential pathway.BMC medical ethics · 2026Article
- Living kidney donation prior to euthanasia: medical, psychological and ethical considerations.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
- Organ donation after euthanasia starting at home: a mixed-methods study of preliminary nationwide Dutch experiences.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
- Results of Kidney Transplantation from Donors Following Euthanasia in the Netherlands: Benchmarking Science and Ethical Challenge.Transplant international : official journal of the European Society for Organ Transplantation · 2024Article
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7 authors.
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Abstract
The outcome of kidneys transplanted following organ donation after euthanasia (ODE) remains unclear. This study analyzed all kidney transplantations in the Netherlands from January 2012 to December 2021, comparing the outcomes following ODE, donation after circulatory death (DCD-III), and donation after brain death (DBD). 9,208 kidney transplantations were performed: 148 ODE, 2118 DCD-III, and 1845 DBD. Initial graft function was compared between these categories. Immediate graft function, delayed graft function and primary non-function in ODE kidney recipients were 76%, 22%, and 2%, respectively, 47%, 50% and 3% in DCD-III kidney recipients and 73%, 25%, and 2% in DBD kidney recipients (overall p-value: p < 0.001). The number of kidneys transplanted over a median follow-up period of 4.0 years (IQR 2.0-6.6), was 1810, including 72 ODE, 958 DCD-III and 780 DBD kidneys. In this period, 213 grafts (11.8%) failed [7 grafts (9.7%) from ODE donors, 93 grafts (9.7%) from DCD-III donors, and 113 grafts (14.5%) from DBD donors]. Kidneys transplanted after euthanasia have a good immediate graft function, a comparable longitudinal 10 years eGFR, and similar graft failure hazard to kidneys from DCD-III and DBD. Kidney transplantation following ODE is a valuable and safe contribution to the donor pool.
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