Evidence map›Paper›PMID 39494220›Full record

ArticleResearch (Washington, D.C.)2024

Noninvasive Monitoring of Programmed Death-Ligand 2 Expression with Positron Emission Tomography using

Yajie Zhao, Xiaoqin Yin, Ming Zhou, Wanqian Rao, Xuan Ji, Xiaobo Wang, XiaoXiong Xiao, Shuo Hu

Abstract read
In one paragraph

Article in Research (Washington, D.C.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. A high-affinity CEA-targeted nanobody forJournal of nanobiotechnology · 2025
    Article
  2. Synthesis and Evaluation of [Pharmaceutics · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yajie ZhaoDepartment of Nuclear Medicine, Xiangya Hospital, Central South University, Changsha 410008, China.
Xiaoqin YinDepartment of Nuclear Medicine, Xiangya Hospital, Central South University, Changsha 410008, China.
Ming ZhouDepartment of Nuclear Medicine, Xiangya Hospital, Central South University, Changsha 410008, China.
Wanqian RaoDepartment of Nuclear Medicine, Xiangya Hospital, Central South University, Changsha 410008, China.
Xuan JiDepartment of Periodontology, Suzhou Stomatological Hospital, Suzhou, Jiangsu 215026, China.
Xiaobo WangDepartment of Nuclear Medicine and State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.
XiaoXiong XiaoDepartment of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha 410008, China.
Shuo HuDepartment of Nuclear Medicine, Xiangya Hospital, Central South University, Changsha 410008, China.ORCID https://orcid.org/0000-0003-0998-8943

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While the expression of programmed death ligand-1 (PD-L1) is associated with response to immune therapy, PD-L1-negative patients may still benefit from immune treatment. Programmed death ligand-2 (PD-L2), another crucial immune checkpoint molecule interacting with PD-1, correlates with the efficacy of various tumor immune therapies. This study investigates the expression of PD-L2 in non-small cell lung cancer (NSCLC) patients following anti-PD-1 therapy and its predictive value for clinical survival outcomes. Additionally, we explore the noninvasive, real-time, and dynamic quantitative analysis potential of PD-L2 positron emission tomography (PET) imaging in transplanted tumors. We utilized [

Identifiers

PMID39494220
PMCPMC11528066

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.