Evidence map›Paper›PMID 39494084›Full record

SynthesisFrontiers in public health2024

Performance of self-performed SARS-CoV-2 rapid antigen test: a systematic review and meta-analysis.

Peiling Cai, Junren Wang, Peng Ye, Yarong Zhang, Mengping Wang, Ronglian Guo, Hongying Zhao

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Frontiers in public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Peiling Cai *Department of Anatomy and Histology, School of Preclinical Medicine, Chengdu University, Chengdu, Sichuan, China.
Junren Wang *Department of Anatomy and Histology, School of Preclinical Medicine, Chengdu University, Chengdu, Sichuan, China.
Peng YeDepartment of Anatomy and Histology, School of Preclinical Medicine, Chengdu University, Chengdu, Sichuan, China.
Yarong ZhangThe First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shannxi, China.
Mengping WangDepartment of Anatomy and Histology, School of Preclinical Medicine, Chengdu University, Chengdu, Sichuan, China.
Ronglian GuoDepartment of Pediatrics, Zhongshan Hospital of Xiamen University, Xiamen University, Xiamen, Fujian, China.
Hongying ZhaoDepartment of Pediatrics, Zhongshan Hospital of Xiamen University, Xiamen University, Xiamen, Fujian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The aim of this study was to investigate the accuracy of self-tested SARS-CoV-2 rapid antigen tests. Methods: Databases of Pubmed, Embase, and Cochrane Library were searched for original studies investigating accuracy of self-tested SARS-CoV-2 rapid antigen tests, with RT-PCR as "gold standard." Results: Forty-five eligible studies were found after database searching and screening using pre-defined criteria. The accuracy results from 50,897 suspected COVID-19 patients were pooled, and the overall sensitivity, specificity and diagnostic odds ratio were 0.77, 1.00, and 625.95, respectively. Subgroup analysis showed higher sensitivity of rapid antigen tests in subgroups of Abbott Panbio, self-collected nasal swab samples, and use of nasopharyngeal or oropharyngeal swab and lower Ct cutoff value in RT-PCR. Conclusion: Fully self-performed SARS-CoV-2 rapid antigen tests showed overall high accuracy compared to "gold standard," and are reliable surrogates for the standard test of COVID-19 using nasopharyngeal or oropharyngeal samples and RT-PCR.

Indexed as

COVID-19COVID-19 Serological TestingRapid Diagnostic TestsSelf-TestingAntigens, ViralHumansNasopharynxSARS-CoV-2Sensitivity and SpecificityAntigens, ViralCOVID-19diagnostic accuracyrapid antigen testSARS-CoV-2self-test

Identifiers

PMID39494084
PMCPMC11527648

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.