Evidence map›Paper›PMID 39493675›Full record

ArticleBMJ neurology open2024

Minimising the rate of vascular complications in Deep Brain Stimulation surgery for the management of Parkinson's disease: a single-centre 600-patient case series.

Raymond Cook, Nyssa Chennell Dutton, Peter A Silburn, Linton J Meagher, George Fracchia, Nathan Anderson, Glen Cooper, Hoang-Mai Dinh, Stuart J Cook, Paul Silberstein

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In one paragraph

Article in BMJ neurology open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Raymond CookNeurosurgery, North Shore Private Hospital, Sydney, NSW, Australia.
Nyssa Chennell DuttonPhysiotherapy, North Shore Private Hospital, Sydney, New South Wales, Australia.ORCID 0009-0008-9024-2463
Peter A SilburnMovement Neuroscience Program, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia.
Linton J MeagherNeuropsychiatry, North Shore Private Hospital, Sydney, NSW, Australia.
George FracchiaNeurosurgery, North Shore Private Hospital, Sydney, NSW, Australia.
Nathan AndersonRadiology, North Shore Private Hospital, Sydney, New South Wales, Australia.
Glen CooperRadiology, North Shore Private Hospital, Sydney, New South Wales, Australia.
Hoang-Mai DinhNeurology, Royal North Shore Hospital, Sydney, New South Wales, Australia.
Stuart J CookUniversity College Dublin, Dublin, Ireland.ORCID 0000-0003-3862-0048
Paul SilbersteinNeurology, Royal North Shore Hospital, Sydney, New South Wales, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Deep Brain Stimulation (DBS) is an effective, yet underused therapy for people living with Parkinson's disease (PD) in whom tremor, motor fluctuations and/or dyskinesia are not satisfactorily controlled by oral medical therapy. Fear of vascular complications related to the operative procedure remains a strong reason for both the referrer and patient reluctance. We review the incidence of vascular complications in the first 600 patients with Parkinson's disease treated at our centre by a single neurologist/neurosurgical team. Methods: Surgical data routinely collected for patients who underwent DBS implantation for the management of PD between the years 2001-2023 was retrospectively reviewed. Incidences of vascular complication were analysed in detail, examining causal factors. Results: Including reimplantations, 600 consecutive DBS patients underwent implantation with 1222 DBS electrodes. Three patients (0.50%) experienced vascular complications. Conclusion: This vascular complication rate is at the low end of that reported in the literature. Risk mitigation strategies discussed include a consistent neurosurgical team, dual methodology target and trajectory planning, control of cerebrospinal fluid egress during the procedure, use of a specialised microelectrode recording (MER)/macrostimulation electrode without an introducing brain cannula and low number of MER passes. A reduced vascular complication rate may improve the acceptability of DBS therapy for both patients and referrers.

Indexed as

MOVEMENT DISORDERSNEUROSURGERYPARKINSON'S DISEASESTROKE

Identifiers

PMID39493675
PMCPMC11529736

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.