SynthesisFrontiers in oncology2024
Evolving trends in oral cancer burden in Europe: a systematic review.
Synthesis in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Incidence of Malignant Oral Cavity Tumors in the Republic of Serbia: Trend Analysis (1999-2020) and Projections to 2040.Medicina (Kaunas, Lithuania) · 2026Article
- Exploring betanin regulatory impact on TGF-β and PI3K/AKT pathways in oral cancer.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Article
- Radiologic 3D tumor volume predicts cervical metastasis in oral squamous cell carcinoma.Clinical oral investigations · 2026Article
- Novel Disease-Specific Panel of Salivary microRNAs for the Detection of Oral Squamous Cell Carcinoma from Early Invasion to Stage IV Disease.International journal of molecular sciences · 2026Article
- Burden, Trends and Projection of Lip and Oral Cavity Cancer in Central, Eastern and Western Europe: From the Global Burden of Disease 2023 Study.International dental journal · 2026Article
- Geographic inequalities and gender-specific trends in oropharyngeal cancer mortality in Spain.Medicina oral, patologia oral y cirugia bucal · 2026Article
- Explainable vision transformer framework for multi-class classification and prognostic interpretation of oral cancer in histopathology images.Discover oncology · 2026Article
- Global quality of care trends for lip and oral cavity cancer: A quality of care index analysis, 1990-2021.Preventive medicine reports · 2026Article
- HPV-positive cancers at uncommon sites: a narrative review.Oncology reviews · 2026Review
- Article
- Frequency of Oral Squamous Cell Carcinoma in Two Public Hospitals in Peru: A Ten-Year Retrospective Study.Oral health & preventive dentistry · 2025Article
- Treatment Strategies for Oral Cavity and Oropharyngeal Squamous Cell Carcinoma: A Systematic Review of Neoadjuvant Chemotherapy and Transoral Robotic Surgery.Journal of pharmacy & bioallied sciences · 2025Article
- Global, regional, and national burden of lip and oral cavity cancer and projections to 2036.BMC cancer · 2025Article
- Epidemiology of Oral Cancer in Cyprus: A Population-Based Cancer Registry Study and Policy Implications.Cureus · 2025Article
- Novel receptor tyrosine kinase-targeted strategies to overcome resistance in oral squamous cell carcinoma.Pharmacological reports : PR · 2025Review
- [miR-302a-3p targeting lysosomal-associated membrane protein 5 inhibits the invasion and metastasis of oral squamous cell carcinoma].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2025Article
- [Lip and oral cancers in East Asia from 1990 to 2035: trends of disease burden and future projections].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025Article
- The Efficacy of Curcumin-Mediated Photodynamic Therapy in the Treatment of Oral Squamous Cell Carcinoma: A Systematic Review of In Vitro Studies.Life (Basel, Switzerland) · 2025Review
- ANAPC10 expression predicts poor prognosis in oral squamous cell carcinoma and promotes tumor growth via the PI3K/AKT/mTOR pathway.Discover oncology · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Oral cavity cancer (OCC), primarily oral squamous cell carcinoma (OSCC), is a growing concern in Europe, particularly among younger populations. Preventable lifestyle factors and social determinants of health contribute significantly to the disease burden. Limited access to healthcare and delayed diagnoses further complicate treatment and reduce survival rates. Methods: This systematic literature review adhered to PRISMA guidelines to explore trends in OSCC epidemiology, etiology, diagnosis, treatment, and survival across Europe. A comprehensive search strategy using PubMed, GLOBOCAN data, and the EUROCARE-5 study identified relevant articles focusing on human populations in Europe with a primary interest in OSCC epidemiology. Only peer-reviewed publications in English with full-text access were included. Results: This study investigated the burden of OSCC across Europe, revealing variations in incidence, mortality, and prognosis. Eastern and Central Europe displayed the highest burden. Males exhibited a significantly higher risk compared to females. Age-related disparities existed in life expectancy and time to achieve favorable outcomes. HPV emerged as a growing risk factor for oropharyngeal cancer. Public health strategies should target modifiable risk factors and improve early detection. Conclusion: This review reveals concerning disparities in European OSCC. Region, sex, and age all influence burden and prognosis. Future research should focus on controlling risk factors and personalized medicine to optimize treatment. This will lead to a Europe with reduced OSCC incidence and demonstrably better patient outcomes.
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