ArticleCureus2024
Culture-Negative Endocarditis Complicated by Cerebral Abscesses Due to Streptococcus gordonii: A Diagnostic Odyssey.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endocarditis is a serious diagnostic entity that carries a high rate of morbidity and mortality, with complications including heart failure, septic embolization, brain abscesses, and stroke. Blood culture-negative endocarditis (BCNE) represents a particularly challenging clinical scenario where the causative organism is undetectable, either due to being difficult to culture or due to the empiric administration of antimicrobial agents. This entity generally results in delayed diagnosis and treatment of endocarditis, with a potential increase in the rate of complications. In this report, we present a case of multiple brain abscesses resulting from BCNE, where the causative organism - and hence effective treatment - was only identified with the implementation of modern molecular diagnostic techniques like Karius, isothermal amplification methods, etc. We also highlight the specific entities of BCNE, its pathogenesis, and differential diagnosis, as well as the effective diagnostic and therapeutic options available to date.
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