Evidence map›Paper›PMID 39493108›Full record

ArticleCureus2024

Recurrent Thrombosis in a Very Elderly Patient With Dementia, Atrial Fibrillation, and Idiopathic Thrombocytopenic Purpura on Eltrombopag Treatment.

Satoshi Kurisu, Hitoshi Fujiwara, Takeshi Shimomura

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Satoshi KurisuDepartment of Cardiology, National Hospital Organization Hiroshima-Nishi Medical Center, Otake, JPN.
Hitoshi FujiwaraDepartment of Cardiology, National Hospital Organization Hiroshima-Nishi Medical Center, Otake, JPN.
Takeshi ShimomuraDepartment of Haematology, National Hospital Organization Hiroshima-Nishi Medical Center, Otake, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Idiopathic thrombocytopenic purpura (ITP) is an autoimmune disorder, leading to an increased bruising and bleeding tendency. Eltrombopag, a thrombopoietin receptor agonist, is an effective treatment option even in elderly patients with ITP. In this report, we present a case of recurrent thrombosis, presenting as acute myocardial infarction and cerebral infarction, in a very elderly patient with dementia, atrial fibrillation, and ITP on eltrombopag treatment. Multiple comorbidities with thrombosis and bleeding risks posed a therapeutic dilemma. Conditions unique to the elderly, such as cognitive impairment or frailty, led to a delayed diagnosis. This case gives an insight into how to manage a practical therapeutic problem in such a case. Physicians need to understand conditions unique to the elderly, such as cognitive impairment, frailty, or quality of life that influence treatment goals. These efforts can help provide health benefits while minimizing treatment risks, especially in elderly patients with multiple comorbidities.

Indexed as

anticoagulationbleedingcoronary embolismmyocardial infarctionthrombopoietin receptor agonist

Identifiers

PMID39493108
PMCPMC11531366

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.