Evidence map›Paper›PMID 39492951›Full record

ArticleBiomedical signal processing and control2025

Maternal ECG-Guided Neural Network for Improved Fetal Electrocardiogram Extraction.

Ko-Tsung Hsu, Trong N Nguyen, Anita N Krishnan, Rathinaswamy Govindan, Raj Shekhar

Abstract read
In one paragraph

Article in Biomedical signal processing and control, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ko-Tsung HsuChildren's National Hospital, Washington DC 20010 USA.
Trong N NguyenAusculTech Dx LLC, Silver Spring, MD 20902 USA.
Anita N KrishnanChildren's National Hospital, Washington DC 20010 USA.
Rathinaswamy GovindanChildren's National Hospital, Washington DC 20010 USA.
Raj ShekharChildren's National Hospital, Washington DC 20010 USA.

Funding

Development of a portable beat-to-beat fetal ECG systemR41HD109072 · NICHD · AUSCULTECH DX, LLC · PI KRISHNAN, ANITA, SHEKHAR, RAJ · 2023 to 2023
$256k
NICHD NIH HHS R41 HD109072
6 · The paper itself

Abstract

Historically, acquiring a reliable and accurate non-invasive fetal electrocardiogram has several significant challenges in both data acquisition and attenuation of maternal signals. These barriers include maternal physical/physiological parameters, hardware sensitivity, and the effectiveness of signal processing algorithms in separating maternal and fetal electrocardiograms. In this paper, we focus on the evaluation of signal-processing algorithms. Here, we propose a learning-based method based on the integration of maternal electrocardiogram acquired as guidance for transabdominal fetal electrocardiogram signal extraction. The results demonstrate that incorporating the maternal electrocardiogram signal as input for training the neural network outperforms the network solely trained using information from the abdominal electrocardiogram. This indicates that leveraging the maternal electrocardiogram serves as a suitable prior for effectively attenuating maternal electrocardiogram from the abdominal electrocardiogram.

Indexed as

deep learningFetal electrocardiogramneural networknon-invasive ECG extractionsignal processingsource separation

Identifiers

PMID39492951
PMCPMC11525986

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.