Evidence map›Paper›PMID 39492746›Full record

ArticleSoft matter2024

Mapping deformation dynamics to composition of topologically-active DNA blends.

Karthik R Peddireddy, Ryan McGorty, Rae M Robertson-Anderson

Abstract read
In one paragraph

Article in Soft matter, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Karthik R PeddireddyDepartment of Physics and Biophysics, University of San Diego, 5998 Alcala Park, San Diego, CA 92110, USA. randerson@sandiego.edu.ORCID http://orcid.org/0000-0003-4282-5484
Ryan McGortyDepartment of Physics and Biophysics, University of San Diego, 5998 Alcala Park, San Diego, CA 92110, USA. randerson@sandiego.edu.ORCID http://orcid.org/0000-0002-6577-060X
Rae M Robertson-AndersonDepartment of Physics and Biophysics, University of San Diego, 5998 Alcala Park, San Diego, CA 92110, USA. randerson@sandiego.edu.ORCID http://orcid.org/0000-0003-4475-4667

Funding

Biomimetic cytoskeleton and advanced microscopy to reveal intracellular DNA dynamics and distributionsR15GM123420 · NIGMS · UNIVERSITY OF SAN DIEGO · PI MCGORTY, RYAN, ROBERTSON-ANDERSON, RAE MARIE · 2017 to 2022
$939k
NIGMS NIH HHS R15 GM123420
6 · The paper itself

Abstract

Blends of circular and linear polymers have fascinated researchers for decades, and the role of topology on their stress response and dynamics remains fervently debated. While linear polymers adopt larger coil sizes and form stronger, more pervasive entanglements than their circular counterparts, threading of circular polymers by linear chains can introduce persistent constraints that dramatically decrease mobility, leading to emergent rheological properties in blends. However, the complex interplay between topology-dependent polymer overlap and threading propensity, along with the large amounts of material required to sample many compositions, has limited the ability to experimentally map stress response to composition with high resolution. Moreover, the role of supercoiling on the response of circular-linear blends remains poorly understood. Here, we leverage

Indexed as

DNADNA, SuperhelicalNucleic Acid ConformationOptical TweezersStress, MechanicalDNADNA, Superhelical

Identifiers

PMID39492746
PMCPMC11613941

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.