Evidence map›Paper›PMID 39492590›Full record

Observational studyAndrology2025

Sexual dysfunctions in inflammatory bowel disease: role of Mediterranean diet and quality of life.

Lorenzo Romano, Mariano Fonticelli, Agnese Miranda, Kateryna Priadko, Luigi Napolitano, Felice Crocetto, Biagio Barone, Davide Arcaniolo, Lorenzo Spirito, Celeste Manfredi and 14 more

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Andrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Observational
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Lorenzo RomanoDepartment of Neurosciences, Reproductive Sciences and Odontostomatology and Urology Unit, Federico II University, Naples, Italy.
Mariano FonticelliDepartment of Precision Medicine and Hepatogastroenterology Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
Agnese MirandaGastroenterology Unit, AORN V. Monaldi, Naples, Italy.
Kateryna PriadkoDepartment of Precision Medicine and Hepatogastroenterology Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
Luigi NapolitanoDepartment of Neurosciences, Reproductive Sciences and Odontostomatology and Urology Unit, Federico II University, Naples, Italy.
Felice CrocettoDepartment of Neurosciences, Reproductive Sciences and Odontostomatology and Urology Unit, Federico II University, Naples, Italy.ORCID 0000-0002-4315-7660
Biagio BaroneDepartment of Neurosciences, Reproductive Sciences and Odontostomatology and Urology Unit, Federico II University, Naples, Italy.ORCID 0000-0003-4884-132X
Davide ArcanioloDepartment of Woman, Child and General and Specialized Surgery and Urology Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
Lorenzo SpiritoDepartment of Woman, Child and General and Specialized Surgery and Urology Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.ORCID 0000-0003-1175-8637
Celeste ManfrediDepartment of Woman, Child and General and Specialized Surgery and Urology Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
Antonietta Gerarda GravinaDepartment of Precision Medicine and Hepatogastroenterology Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
Carmine SciorioUrology Unit, A. Manzoni General Hospital, Lecco, Italy.
Debora CompareGastroenterology Unit, Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy.
Raffaele MelinaEndoscopy Unit, AORN G. Moscati, Avellino, Italy.
Dolores SgambatoEndoscopy Unit, AORN G. Moscati, Avellino, Italy.
Ambrogio OrlandoIBD Unit, AO Villa Sofia-Cervello, Palermo, Italy.
Silvia CalderoneIBD Unit, AO Villa Sofia-Cervello, Palermo, Italy.
Olga Maria NardoneGastroenterology, Department of Public Health, Federico II University, Naples, Italy.
Gerardo NardoneGastroenterology Unit, Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy.
Paola CarusoDivision of Endocrinology and Metabolic Diseases, University Hospital of Campania "Luigi Vanvitelli", Naples, Italy.ORCID 0000-0002-4756-2022
Katherine EspositoDepartment of Advanced Medical and Surgical Sciences, Division of Endocrinology and Metabolic Diseases, University of Campania "Luigi Vanvitelli", Naples, Italy.
Marco De SioDepartment of Woman, Child and General and Specialized Surgery and Urology Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
Marco RomanoDepartment of Precision Medicine and Hepatogastroenterology Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
Maria Ida MaiorinoDepartment of Advanced Medical and Surgical Sciences, Division of Endocrinology and Metabolic Diseases, University of Campania "Luigi Vanvitelli", Naples, Italy.ORCID 0000-0003-4659-7546

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDietary factors and chronic gastrointestinal diseases are frequent determinants of sexual dysfunctions (SD). Whether inflammatory bowel diseases (IBD) are associated with SD is not well known as well as the role of diet and quality of life (QoL).

objectivesTo evaluate the prevalence of SD in a cohort of IBD patients and assess the role of clinical-demographic variables, adherence to Mediterranean diet (MD) and QoL. MATERIALS AND

methodsThis is a cross-sectional observational study involving 301 patients (134 females and 167 males); 119 had Crohn's Disease and 182 had ulcerative colitis. SD were assessed through the Female Sexual Function Index (FSFI) and the International Index of Erectile Function (IIEF). Adherence to MD was evaluated by the MD Score. QoL was investigated by the 12-item Short-Form Health Survey (SF-12) which yields summary scores of physical (PCS) and mental (MCS) health. Multiple logistic regression was used to identify predictors of SD.

resultsPrevalence of SD in females was 61.9%, while 52.1% of males had erectile dysfunction. No differences in the prevalence of SD were found between CD and UC in both males and females. IBD activity, as defined by patient-reported outcomes, was significantly associated with SD in both sexes. In females, MD adherence score (OR 0.8, 95% CI 0.653-0.974, p = 0.027), PCS (OR = 0.936, CI 95% = 0.891-0.983, p = 0.008), and MCS (OR 0.9, 95% CI 0.906-0.985, p = 0.008) were protective against SD, whereas in males a higher PCS was associated with a lower probability of SD (OR 0.9, 95% CI 0.891-0.978, p = 0.004) DISCUSSION: IBD patients had a significant prevalence of SD which occurred more frequently in females than in males. Disease activity is associated with a higher likelihood of SD in both sexes, whereas dietary factors are differentially associated with SD in males and females. A better QoL is associated with a lower risk of SD.

conclusionSD is prevalent among men and women with IBD. Adherence to MD, PCS and MCS in females as well as PCS in males were protective against SD. The assessment of sexual function in IBD patients could be relevant in order to reach an early diagnosis and a timely treatment.

Indexed as

Colitis, UlcerativeCrohn DiseaseDiet, MediterraneanInflammatory Bowel DiseasesQuality of LifeSexual Dysfunction, PhysiologicalAdultCross-Sectional StudiesErectile DysfunctionFemaleHumansMaleMiddle AgedPrevalenceFSFIIIEFinflammatory bowel diseaseMediterranean dietquality of lifesexual dysfunctions

Identifiers

PMID39492590
PMCPMC12476212

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.