ArticleThe Journal of organic chemistry2024
Three-Component 1,2-Dioxygenation of 1,3-Dienes Using Carboxylic Acids and TEMPO.
Article in The Journal of organic chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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Who cites it
2 citing papers in PubMed.
- Organic Photoredox-Catalyzed TEMPO Disproportionation: Development of a Mild Platform for In Situ Oxoammonium Ion Formation.The Journal of organic chemistry · 2026Article
- Copper-Catalyzed 1,2-Diazidation and 1,2-Azidooxygenation of 1,3-Dienes: Three Divergent Protocols Using Zhdankin's Reagent.The Journal of organic chemistry · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A mild, metal-free 1,2-dioxygenation of 1,3-dienes using TEMPO and carboxylic acids is reported. This method includes examples for a variety of 1,3-dienes as well as aliphatic and aromatic carboxylic acids. This reaction also demonstrates complete site- and regioselectivity in the oxygen addition. Furthermore, extensive derivatization of the differential oxygen groups in the product has been demonstrated, including reduction of the remaining alkene to access alkyl, vicinally dioxygenated scaffolds. Finally, this reaction is shown both experimentally and computationally to occur through carboxylic acid-driven disproportionation of TEMPO.
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Registered trials
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