Evidence map›Paper›PMID 39491901›Full record

ReviewCurrent opinion in neurobiology2023

A goal pointer for a cognitive map in the orbitofrontal cortex.

Raunak Basu, Hiroshi T Ito

Abstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Raunak BasuEdmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem, Jerusalem 9190401, Israel. Electronic address: raunak.basu@mail.huji.ac.il.
Hiroshi T ItoMax Planck Institute for Brain Research, Frankfurt am Main 60438, Germany. Electronic address: hiroshi.ito@brain.mpg.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Knowing where you are and where you go is a prerequisite for planning a goal-directed journey. The discovery of spatially tuned neurons in the hippocampus and parahippocampal cortices provides a mechanism by which the brain pinpoints an animal's own position in an environment. By contrast, how the brain encodes a remote navigational goal remained largely obscure until recently. In this review, we discuss algorithmic challenges and requirements for the brain to form a representation of a remote navigational goal at which an animal is not present. We then highlight a line of evidence that neurons in the orbitofrontal cortex (OFC) represent a goal location persistently while an animal navigates to this destination. Finally, we propose a new perspective of navigation research opened by this recently reported brain's goal map.

Identifiers

PMID39491901
PMCPMC10711504

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.