Evidence map›Paper›PMID 39491887›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

Striatal Cholinergic Interneurons Control Physical Nicotine Withdrawal via Muscarinic Receptor Signaling.

Baeksun Kim, Han Ah Kim, Junsung Woo, Hyeon-Jeong Lee, Tae Kyoo Kim, Hophil Min, C Justin Lee, Heh-In Im

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Baeksun KimCenter for Brain Function, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.
Han Ah KimCenter for Brain Function, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.
Junsung WooCenter for Glia-Neuron Interaction, Brain Science Institute, KIST, Seoul, 02792, Republic of Korea.
Hyeon-Jeong LeeDoping Control Center, KIST, Seoul, 02792, Republic of Korea.
Tae Kyoo KimCenter for Brain Function, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.
Hophil MinDivision of Bio-Medical Science & Technology, KIST School, Korea National University of Science and Technology (UST), Seoul, 02792, Republic of Korea.
C Justin LeeCenter for Glia-Neuron Interaction, Brain Science Institute, KIST, Seoul, 02792, Republic of Korea.
Heh-In ImCenter for Brain Function, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.ORCID 0000-0002-4763-5009

Funding

Korea Institute of Science and Technology 2E32851National Institute of Food and Drug Safety Evaluation RS-2024-00332024National Research Foundation of Korea 2020R1A2C2004610National Research Foundation of Korea 2022R1A6A3A01087565
6 · The paper itself

Abstract

Striatal cholinergic interneurons (ChIs) provide acetylcholine tone to the striatum and govern motor functions. Nicotine withdrawal elicits physical symptoms that dysregulate motor behavior. Here, the role of striatal ChIs in physical nicotine withdrawal is investigated. Mice under RNAi-dependent genetic inhibition of striatal ChIs (ChI

Indexed as

Corpus StriatumInterneuronsNicotineReceptors, MuscarinicSignal TransductionSubstance Withdrawal SyndromeAnimalsDisease Models, AnimalMaleMiceMice, Inbred C57BLNicotineReceptors, Muscariniccholinergic interneuronsdopaminedorsal striatummuscarinic receptorneural activitynicotine withdrawalsomatic signs

Identifiers

PMID39491887
PMCPMC11653618

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.