Evidence map›Paper›PMID 39491610›Full record

ArticleJournal of cardiac failure2025

Disruptions in Sleep Health and Independent Associations with Psychological Distress in Close Family Members of Cardiac Arrest Survivors: A Prospective Study.

Isabella M Tincher, Danielle A Rojas, Mina Yuan, Sabine Abukhadra, Christine E Deforge, S Justin Thomas, Kristin Flanary, Daichi Shimbo, Nour Makarem, Bernard P Chang and 1 more

Abstract read
In one paragraph

Article in Journal of cardiac failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Article
  4. Resuscitation plus · 2025
    Article
  5. Psychological and behavioral dimensions in cardiac arrest survivors and their families: A state-of-the-art review.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Isabella M TincherDepartment of Neurology, Columbia University Irving Medical Center, New York, New York.
Danielle A RojasDepartment of Neurology, Columbia University Irving Medical Center, New York, New York.
Mina YuanColumbia University Vagelos College of Physicians and Surgeons, New York, New York.
Sabine AbukhadraWake Forest School of Medicine, Winston-Salem, North Carolina.
Christine E DeforgeColumbia University School of Nursing, New York, New York.
S Justin ThomasDepartment of Psychiatry & Behavioral Neurobiology, The University of Alabama at Birmingham, Birmingham, Alabama.
Kristin FlanaryCardiac Arrest Family Member Stakeholder & Advocate, Portland, Oregon.
Daichi ShimboDivision of Cardiology, Columbia University Irving Medical Center, New York, New York.
Nour MakaremDepartment of Epidemiology, Mailman School of Public Health, Columbia University Irving Medical Center, New York, New York.
Bernard P ChangDepartment of Emergency Medicine, Columbia University Irving Medical Center, New York, New York.
Sachin AgarwalDepartment of Neurology, Columbia University Irving Medical Center, New York, New York. Electronic address: sa2512@columbia.edu.

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Project 3-Community Health workers United to Reduce Colorectal cancer and CVD among people at Higher risk (CHURCH)P50MD017341 · NIMHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAKAREM, NOUR · 2021 to 2025
$23.9M
NRSA Training CoreTL1TR001875 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SPANN, MARISA N, TAYLOR, JACQUELYN Y · 2016 to 2025
$8.9M
SHORT-TERM TRAINING: STUDENTS IN PROFESSIONAL SCHOOLST35HL007616 · NHLBI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI RUDOLPH L LEIBEL, Markus Y Mapara · 1985 to 2026
$4.4M
The Identification of Modifiable Emergency Department and Sleep Factors Contributing to Psychological and Cardiovascular Risk in CliniciansR01HL146911 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CHANG, BERNARD P., SHECHTER, ARI · 2020 to 2024
$4.3M
Psychological symptoms in healthcare workers following the COVID-19 pandemic and relationship to long-term cardiovascular riskR01HL157341 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Jeffrey Lee Birk, Bernard P. Chang · 2022 to 2026
$3.8M
Testing a rapid outpatient management strategy on PTSD, cardiovascular and rehospitalization risk in TIA and minor stroke survivors evaluated in the Emergency DepartmentR01HL141811 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CHANG, BERNARD P. · 2018 to 2022
$3.5M
Characterize psychological and behavioral dimensions of cardiac arrest survivorship, and their association with 1-year mortality, cardiovascular disease risk, and health-related quality of lifeR01HL153311 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI AGARWAL, SACHIN · 2021 to 2024
$3.1M
CIRCADIAN PATTERN OF REST-ACTIVITY RHYTHMS AND BLOOD PRESSURE AND THE UNDERLYINGR00HL148511 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAKAREM, NOUR · 2021 to 2023
$809k
NCATS NIH HHS TL1 TR001875NCATS NIH HHS UL1 TR001873NHLBI NIH HHS R00 HL148511NHLBI NIH HHS R01 HL141811NHLBI NIH HHS R01 HL146911NHLBI NIH HHS R01 HL153311NHLBI NIH HHS R01 HL157341NHLBI NIH HHS T35 HL007616NIMHD NIH HHS P50 MD017341
6 · The paper itself

Abstract

backgroundWhile recent guidelines have noted the deleterious effects of poor sleep on cardiovascular health, the upstream impact of cardiac arrest-induced psychological distress on sleep health metrics among families of cardiac arrest survivors remains unknown.

methodsSleep health of close family members of consecutive patients with cardiac arrest admitted to an academic center (August 16, 2021-June 28, 2023) was self-reported using the Pittsburgh Sleep Quality Index (PSQI). The baseline PSQI, focused on sleep in the month before cardiac arrest, was administered during hospitalization and repeated 1 month after cardiac arrest alongside the Patient Health Questionnaire-8 (PHQ-8) to assess depression severity. Multivariable linear regressions analyzed associations between total PHQ-8 scores and changes in global PSQI scores between baseline and 1 month, with higher scores indicating deterioration. A prioritization exercise explored potential interventions categorized into the family's information and well-being needs to reduce psychological distress.

resultsIn our sample of 102 close family members (mean age 52 ± 15 years, 70% female, 21% Black, 33% Hispanic), mean global PSQI scores showed a significant decline between baseline and 1 month after cardiac arrest (6.2 ± 3.8 vs. 7.4 ± 4.1; P < .01). This deterioration was notable for sleep quality, duration, and daytime dysfunction. Higher PHQ-8 scores were significantly associated with higher change in PSQI scores after adjusting for family members' age, sex, race/ethnicity, prior psychiatric history, and patient's discharge disposition (B = 0.4 [95% CI 0.24-0.48]; P < .01, β = 0.5). Most families expressed a higher priority for information-based interventions over well-being needs to help alleviate psychological distress during the first month following cardiac arrest (76% vs. 34%, P < .01).

conclusionsA significant sleep health decline was observed among close family members of cardiac arrest survivors during the acute period, with psychological distress associated with this disruption. Understanding these temporal associations will help guide the development of targeted interventions to support families during this uncertain time.

Indexed as

FamilyHeart ArrestPsychological DistressSleep QualitySleep Wake DisordersStress, PsychologicalSurvivorsAdultAgedFemaleHumansMaleMiddle AgedProspective StudiesanxietyCardiac arrestcaregiverdepressionpost-traumatic stress disordersleep

Identifiers

PMID39491610
PMCPMC12210521

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.