Evidence map›Paper›PMID 39491038›Full record

Observational studyBMC cancer2024

The optimal timing of breast cancer surgery after COVID-19 infection: an observational study.

Zhao Bi, Wei-Hao Cheng, Wen-Hao Zheng, Tong-Yue Ren, Peng Chen, Yan-Bing Liu, Peng-Fei Qiu, Wei-Li Wang, Yong-Sheng Wang

Abstract readObservational Study
In one paragraph

Observational study in BMC cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhao BiShandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences, Ji Yan Road 440, Jinan, 250000, Shandong Province, People's Republic of China.
Wei-Hao ChengShandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences, Ji Yan Road 440, Jinan, 250000, Shandong Province, People's Republic of China.
Wen-Hao ZhengRizhao Central Hospital, Rizhao, 250000, Shandong, People's Republic of China.
Tong-Yue RenShandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences, Ji Yan Road 440, Jinan, 250000, Shandong Province, People's Republic of China.
Peng ChenShandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences, Ji Yan Road 440, Jinan, 250000, Shandong Province, People's Republic of China.
Yan-Bing LiuShandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences, Ji Yan Road 440, Jinan, 250000, Shandong Province, People's Republic of China.
Peng-Fei QiuShandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences, Ji Yan Road 440, Jinan, 250000, Shandong Province, People's Republic of China.
Wei-Li WangShandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences, Ji Yan Road 440, Jinan, 250000, Shandong Province, People's Republic of China.
Yong-Sheng WangShandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences, Ji Yan Road 440, Jinan, 250000, Shandong Province, People's Republic of China. yswang@sdfmu.edu.cn.

Funding

China Postdoctoral Science Foundation 2022M721987
6 · The paper itself

Abstract

purposeIt is controversial for the optimal time of breast cancer surgery after COVID-19 infection. Purpose was to assess the risk of postoperative complication in breast cancer patients with COVID-19 infection, in order to select optimal surgery timing after COVID-19 infection.

methodsBreast cancer patients infected with COVID-19 and performed surgery between December 20th, 2022 to March 20th, 2023 were included in this prospective study (n = 577). Patients performed surgery between May 1, 2019 to October 1, 2019 were listed as control group (n = 329). They had not been infected with COVID-19 before surgery. Patients were grouped by time of surgery relative to COVID-19 infection. Database was evaluated using logistic regression.

resultsPatients infected with COVID-19 had a higher incidence of complications after surgery compared to that not-COVID-19 infection (6.59% vs. 3.04%). Multivariable logistic analysis demonstrated that timing of surgery was associated with complications (OR = 4.253; 95% CI: 0.855-21.153, P = 0.044). Patients performed surgery within 2 weeks after COVID-19 infection had the highest rates of complication (17.65%) when compared with other groups, while the incidence was decreased into 5.51% when surgery 2 weeks or more after COVID-19 infection. With a median follow-up was 10 months, all patients with complications were recovered without serious complications or death, which had no adverse effect on subsequent anti-tumor therapy.

conclusionsIt needs to be cautious when breast cancer surgery was performed within 2 weeks after COVID-19 infection. Although the incidence of complications in patients undergoing surgery 2 weeks after COVID-19 infection is still slightly high, surgery might be recommended considering urgency of treatment, good prognosis of complications and the lack of influence on subsequent adjuvant therapy.

Indexed as

Breast NeoplasmsCOVID-19Postoperative ComplicationsTime-to-TreatmentAdultAgedFemaleHumansIncidenceMastectomyMiddle AgedProspective StudiesSARS-CoV-2Time FactorsBreast neoplasmsCOVID-19Postoperative complicationsSurgery

Identifiers

PMID39491038
PMCPMC11533406

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.