Evidence map›Paper›PMID 39491020›Full record

ReviewCellular & molecular biology letters2024

Research progress of MUC1 in genitourinary cancers.

Weipu Mao, Houliang Zhang, Keyi Wang, Jiang Geng, Jianping Wu

Abstract readReview
In one paragraph

Review in Cellular & molecular biology letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Weipu Mao *Department of Urology, Affiliated Zhongda Hospital of Southeast University, No. 87 Dingjiaqiao, Gulou District, Nanjing, 210009, Jiangsu, China. maoweipu88@163.com.ORCID http://orcid.org/0000-0002-3878-5224
Houliang Zhang *Department of Urology, Affiliated Zhongda Hospital of Southeast University, No. 87 Dingjiaqiao, Gulou District, Nanjing, 210009, Jiangsu, China.
Keyi WangDepartment of Urology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China. wangkeyi0910@163.com.
Jiang GengDepartment of Urology, Bengbu First People's Hospital, Bengbu, People's Republic of China. gengjiangsn@sina.com.
Jianping WuDepartment of Urology, Affiliated Zhongda Hospital of Southeast University, No. 87 Dingjiaqiao, Gulou District, Nanjing, 210009, Jiangsu, China. doctorwujianping@126.com.

Funding

National Natural Science Foundation of China 82403602Natural Science Foundation of Jiangsu Province BK20230842Natural Science Foundation of Jiangsu Province BK20231422Research Personnel Cultivation Programme of Zhongda Hospital Southeast University CZXM-GSP-RC60
6 · The paper itself

Abstract

MUC1 is a highly glycosylated transmembrane protein with a high molecular weight. It plays a role in lubricating and protecting mucosal epithelium, participates in epithelial cell renewal and differentiation, and regulates cell adhesion, signal transduction, and immune response. MUC1 is expressed in both normal and malignant epithelial cells, and plays an important role in the diagnosis, prognosis prediction and clinical monitoring of a variety of tumors and is expected to be a new therapeutic target. This article reviews the structural features, expression regulation mechanism, and research progress of MUC1 in the development of genitourinary cancers and its clinical applications.

Indexed as

Mucin-1Urogenital NeoplasmsAnimalsGene Expression Regulation, NeoplasticHumansMUC1 protein, humanMucin-1DiagnosisGenitourinary cancersMUC1Therapeutic target

Identifiers

PMID39491020
PMCPMC11533421

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.