Evidence map›Paper›PMID 39490268›Full record

ArticleGait & posture2025

Comparison of gait deviation index (GDI) and gait variability index (GVI) measured by marker-based and markerless motion capture systems in children with cerebral palsy (CP).

Jutharat Poomulna, Brian A Knarr, Vivek Dutt, David C Kingston

Abstract readComparative Study
In one paragraph

Article in Gait & posture, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Jutharat PoomulnaDepartment of Biomechanics, University of Nebraska at Omaha, 6001 Dodge St, Omaha, NE 68182, USA. Electronic address: jpoomulna@unomaha.edu.
Brian A KnarrDepartment of Biomechanics, University of Nebraska at Omaha, 6001 Dodge St, Omaha, NE 68182, USA. Electronic address: bknarr@unomaha.edu.
Vivek DuttUniversity of Nebraska Medical Center, 42nd and, Emile St, Omaha, NE 68198, USA. Electronic address: vdutt@childrensomaha.org.
David C KingstonDepartment of Biomechanics, University of Nebraska at Omaha, 6001 Dodge St, Omaha, NE 68182, USA. Electronic address: dkingston@unomaha.edu.

Funding

Visual control of locomotion in people with Parkinsons diseaseP20GM109090 · NIGMS · UNIVERSITY OF NEBRASKA OMAHA · PI KNARR, BRIAN ANDREW · 2014 to 2023
$20.5M
Mechanics of overground, dry, and aquatic treadmill walking in children & adolescents with cerebral palsyR15HD109666 · NICHD · UNIVERSITY OF NEBRASKA OMAHA · PI KINGSTON, DAVID C · 2022 to 2022
$448k
NICHD NIH HHS R15 HD109666NIGMS NIH HHS P20 GM109090
6 · The paper itself

Abstract

backgroundThe Gait Deviation Index (GDI) is a metric clinicians use to assess overall gait pathology in children with cerebral palsy (CP) by comparing kinematic data to a normative sample. The Gait Variability Index (GVI) is a related metric that quantifies the variability in spatio-temporal variables during gait. The GDI and GVI have been verified using marker-based motion capture approaches, but video-based markerless motion capture has not been compared using these tools in children with CP. RESEARCH QUESTION: Do GDI and GVI scores differ when measured using markerlessTheia3D and a marker-based approach between the more and less affected legs in children with CP?

methodsFifteen children with CP (GMFCS levels I-IV) and 24 typically developing children aged 6-18 years were recruited for this study. Overground walking was performed at a self-selected pace while the pelvis and lower limb kinematics were simultaneously recorded using both motion capture systems. Differences in GDI and GVI scores when considering the effect of system and limb impairment were analyzed using two-way repeated-measures ANOVAs.

resultsGDI scores were 6.9 points lower (p < 0.05) when measured using Theia3D compared to the marker-based approach and 6.8 points lower (p < 0.05) in the more affected limbs than in the less affected limbs. These GDI score differences are considered clinically significant. No differences were identified in GVI scores between systems or limb impairment. Differences in kinematic measurements were found in children with CP, including pelvic tilt, hip flexion/extension, hip rotation, and foot progression angle, where root mean square differences between systems exceeded 10°. SIGNIFICANCE: Theia3D can adequately measure variability in spatio-temporal gait parameters for quantifying GVI scores in children with CP compared to the marker-based approach. However, caution is needed when quantifying lower limb kinematics and interpreting GDI and GVI scores using Theia3D in children with CP.

Indexed as

Cerebral PalsyGait AnalysisGait Disorders, NeurologicAdolescentBiomechanical PhenomenaCase-Control StudiesChildFemaleGaitHumansLower ExtremityMaleMotion CaptureVideo RecordingClinical BiomechanicsGait deviation indexGait variability indexPediatricsTheia3DWalking

Identifiers

PMID39490268
PMCPMC12415537

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.