Evidence map›Paper›PMID 39489927›Full record

ArticleJornal de pediatria

Growth charts of Brazilian girls with Turner syndrome without the use of GH or oxandrolone.

Stela Carpini-Dantas, Gil Guerra-Junior, Andréa Trevas Maciel-Guerra, Denise Barbieri Marmo, Tarsis Paiva Vieira, Carolina Paniago Lopes, Maria Tereza Matias Baptista, André Moreno Morcillo, Sofia Helena Valente de Lemos-Marini

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Jornal de pediatria. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Stela Carpini-DantasDepartamento de Pediatria da Divisão de Endocrinologia Pediátrica, Universidade Estadual de Campinas (UNICAMP), Faculdade de Ciências Médicas (FCM), Campinas, São Paulo, Brazil.
Gil Guerra-JuniorDepartamento de Pediatria da Divisão de Endocrinologia Pediátrica, Universidade Estadual de Campinas (UNICAMP), Faculdade de Ciências Médicas (FCM), Campinas, São Paulo, Brazil. Electronic address: gilguer@unicamp.br.
Andréa Trevas Maciel-GuerraDepartamento de Medicina Translacional, Divisão de Genética Médica e Medicina Genômica, Universidade Estadual de Campinas (UNICAMP), Faculdade de Ciências Médicas (FCM), Campinas, São Paulo, Brazil.
Denise Barbieri MarmoDepartamento de Pediatria da Divisão de Endocrinologia Pediátrica, Universidade Estadual de Campinas (UNICAMP), Faculdade de Ciências Médicas (FCM), Campinas, São Paulo, Brazil.
Tarsis Paiva VieiraDepartamento de Medicina Translacional, Divisão de Genética Médica e Medicina Genômica, Universidade Estadual de Campinas (UNICAMP), Faculdade de Ciências Médicas (FCM), Campinas, São Paulo, Brazil.
Carolina Paniago LopesDepartamento de Pediatria da Divisão de Endocrinologia Pediátrica, Universidade Estadual de Campinas (UNICAMP), Faculdade de Ciências Médicas (FCM), Campinas, São Paulo, Brazil.
Maria Tereza Matias BaptistaDepartamento de Medicina Clínica, Divisão de Endocrinologia, Universidade Estadual de Campinas (UNICAMP), Faculdade de Ciências Médicas (FCM), Campinas, São Paulo, Brazil.
André Moreno MorcilloDepartamento de Pediatria da Divisão de Endocrinologia Pediátrica, Universidade Estadual de Campinas (UNICAMP), Faculdade de Ciências Médicas (FCM), Campinas, São Paulo, Brazil.
Sofia Helena Valente de Lemos-MariniDepartamento de Pediatria da Divisão de Endocrinologia Pediátrica, Universidade Estadual de Campinas (UNICAMP), Faculdade de Ciências Médicas (FCM), Campinas, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe development of specific growth charts for Turner Syndrome (TS) promotes adequate assessment of growth and weight gain, and earlier diagnosis of comorbidities, and may help to analyze the effectiveness of treatments to promote growth and puberty. The aim of this study was to construct a growth chart with the largest possible series of patients with a cytogenetic diagnosis of TS from a Brazilian reference center.

methodsThis is a longitudinal study, with 259 cases of TS born between 1957 and 2014 and followed between 1975 and 2019, without the use of GH or oxandrolone. 3,160 height measurements and 2,918 wt measurements were used, with subsequent calculation of the Body Mass Index (BMI). For data analysis, the "GAMLSS" package of the "R" software was used.

resultsThe mean target height was 157.8 cm (standard deviation 5.2; median 160.4 cm). The mean height of patients with TS at 20 years of age was 145.6 cm (standard deviation 5.9; median 146.7 cm). Height, weight, and BMI by age graphs were developed for TS girls between 2 and 20 years.

conclusionThese growth charts may be used to monitor the growth of girls with TS and to verify the effect of adjuvant treatments on promoting growth.

Indexed as

Growth ChartsTurner SyndromeAdolescentBody HeightBody Mass IndexBody WeightBrazilChildChild, PreschoolFemaleHumansLongitudinal StudiesOxandroloneYoung AdultOxandroloneBody heightBody weightDisorders of sex developmentGrowth chartTurner syndrome

Identifiers

PMID39489927
PMCPMC11889696

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.