Evidence map›Paper›PMID 39489901›Full record

SynthesisThe American journal of clinical nutrition2025

Adulthood dietary and lifestyle patterns and risk of breast cancer: Global Cancer Update Programme (CUP Global) systematic literature review.

Jadwiga Konieczna, Alice Chaplin, Indira Paz-Graniel, Helen Croker, Nerea Becerra-Tomás, Georgios Markozannes, Konstantinos K Tsilidis, Laure Dossus, Esther M Gonzalez-Gil, Yikyung Park and 10 more

Registry-linked trialAbstract readSystematic Review
In one paragraph

Synthesis in The American journal of clinical nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07722442 (Feasibility, Acceptability and Preliminary Efficacy of a Personalised Behavioural Intervention to Improve Adherence to Dietary and Lifestyle Cancer Prevention Recommendations in Adults Attending Breast and Colorectal Cancer Screening Programmes), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07722442 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Feasibility, Acceptability and Preliminary Efficacy of a Personalised Behavioural Intervention to Improve Adherence to Dietary and Lifestyle Cancer Prevention Recommendations in Adults Attending Breast and Colorectal Cancer Screening Programmes: A Three-Arm Randomised Pilot Trial (CANVIA)

TypeinterventionalSponsorFundació d'investigació Sanitària de les Illes BalearsRan2026 to 2028Enrolled162ConditionsDietary and Lifestyle Behaviour ChangeArmsPersonalised baseline feedback report, CANVIA mobile app intervention, Additional health professional support
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Jadwiga KoniecznaResearch Group on Nutritional Epidemiology & Cardiovascular Physiopathology (NUTRECOR), Health Research Institute of the Balearic Islands (IdISBa), University Hospital Son Espases (HUSE), Palma de Mallorca, Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III (ISCIII), Madrid, Spain. Electronic address: jadwiga.konieczna@ssib.es.
Alice ChaplinResearch Group on Nutritional Epidemiology & Cardiovascular Physiopathology (NUTRECOR), Health Research Institute of the Balearic Islands (IdISBa), University Hospital Son Espases (HUSE), Palma de Mallorca, Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III (ISCIII), Madrid, Spain.
Indira Paz-GranielCentro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III (ISCIII), Madrid, Spain; Universitat Rovira i Virgili, Departament de Bioquímica i Biotecnologia, Alimentació, Nutrició, Desenvolupament i Salut Mental ANUT-DSM, Reus, Spain; Institut d'Investigació Pere Virgili (IISPV), Reus, Spain.
Helen CrokerWorld Cancer Research Fund International, London, United Kingdom.
Nerea Becerra-TomásDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.
Georgios MarkozannesDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece.
Konstantinos K TsilidisDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece.
Laure DossusNutrition and Metabolism Branch, International Agency for Research on Cancer, World Health Organization, Lyon, France.
Esther M Gonzalez-GilNutrition and Metabolism Branch, International Agency for Research on Cancer, World Health Organization, Lyon, France.
Yikyung ParkDepartment of Surgery, Washington University in St. Louis, St. Louis, MO, United States.
John KrebsDepartment of Zoology, University of Oxford, Oxford, United Kingdom.
Matty P WeijenbergDepartment of Epidemiology, Maastricht University, Maastricht, Netherlands.
Monica L BaskinUPMC Hillman Cancer Center, Pittsburgh, PA, United States.
Ellen CopsonCancer Sciences Academic Unit, University of Southampton, Southampton, United Kingdom.
Sarah J LewisDepartment of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
Jacob C SeidellFaculty of Science, Department of Health Sciences, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Rajiv ChowdhuryDepartment of Global Health, Florida International University, Miami, FL, United States.
Lynette HillWorld Cancer Research Fund International, London, United Kingdom.
Doris Sm ChanDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.
Dora RomagueraResearch Group on Nutritional Epidemiology & Cardiovascular Physiopathology (NUTRECOR), Health Research Institute of the Balearic Islands (IdISBa), University Hospital Son Espases (HUSE), Palma de Mallorca, Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III (ISCIII), Madrid, Spain.

Funding

Washington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 1999 to 2026
$30.2M
NIDDK NIH HHS P30 DK056341World Health Organization 001
6 · The paper itself

Abstract

backgroundAn increasing number of studies in recent years investigate various dietary and lifestyle patterns and associated breast cancer (BC) risk.

objectivesThis study aimed to comprehensively synthesize and grade the evidence on dietary and lifestyle patterns and BC risk.

methodsDatabases were systematically searched up to 31 March, 2022, for evidence from randomised controlled trials and prospective cohort studies on adherence to a dietary pattern alone or in combination with lifestyle behaviors and incidence of or mortality from primary BC in adult females. Findings in all, premenopausal, and postmenopausal females were descriptively synthesized instead of meta-analyzed due to patterns heterogeneity. An independent Global Cancer Update Programme Expert Panel graded the strength of the evidence.

resultsA total of 84 publications were included. Results for patterns reflecting both a healthy diet and lifestyle were more consistent than for patterns that included diet only. There was strong-probable evidence that a priori World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) and American Cancer Society (ACS) dietary and lifestyle scores may reduce BC risk in all and postmenopausal females, whereas in premenopausal females, less evidence was found contributing to limited-suggestive grade. There was also a limited-suggestive evidence that adherence to the Healthy Lifestyle Index and other diet and lifestyle scores may reduce BC risk in postmenopausal females; a posteriori Western/Meat/Alcohol dietary patterns may increase BC risk in postmenopausal females; and Prudent/Vegetarian/Mediterranean dietary patterns may reduce BC risk in all females. For the remaining patterns, evidence was graded as limited-no conclusions.

conclusionsAdvice to adopt combined aspects of a healthy diet and lifestyle according to WCRF/AICR and ACS scores, encouraging a healthy weight, physical activity, alcohol and smoking avoidance, and a healthy diet rich in fruits, vegetables, (whole)grains and cereals and discouraging red and processed meat, can be proposed to females to lower BC risk. This review was registered at PROSPERO as ID CRD42021270129 (https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021270129) on 28 August, 2021, and further updated on 4 May, 2022, in order to extend the search period.

Indexed as

Breast NeoplasmsDietLife StyleAdultDiet, HealthyExerciseFemaleHumansMiddle AgedPostmenopauseRisk Factorsa posteriori dietary patternsa priori dietary patternsbreast cancer incidencedietary and lifestyle patternsevidence gradinghybrid dietary patternssystematic review

Identifiers

PMID39489901
PMCPMC11747198

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.