Evidence map›Paper›PMID 39489769›Full record

ArticleScientific reports2024

Long-term trends and future projections of larynx cancer burden in China: a comprehensive analysis from 1990 to 2030 using GBD data.

Bijuan Chen, Zhouwei Zhan, Weining Fang, Yahan Zheng, Sisi Yu, Jiali Huang, Jianji Pan, Shaojun Lin, Qiaojuan Guo, Yun Xu

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Burden of early-onset laryngeal cancer in individuals aged 15-49 years: global, regional, and national estimates from the GBD 2021 study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  2. Alterations in Nasal Function Following Total Laryngectomy and Their Clinical Correlates.World journal of otorhinolaryngology - head and neck surgery · 2026
    Article
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  10. The global, regional, and national disease burden of laryngeal cancer attributable to high alcohol use from 1990 to 2021: a global burden of disease study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bijuan ChenDepartment of Radiation Oncology, Fujian Cancer Hospital, Clinical Oncology School of Fujian Medical University, No. 420 Fuma Road, Fuzhou, 350014, Fujian, China.
Zhouwei ZhanDepartment of Medical Oncology, Fujian Cancer Hospital, Clinical Oncology School of Fujian Medical University, No. 420 Fuma Road, Fuzhou, 350014, Fujian, China.
Weining FangDepartment of Radiation Oncology, Fujian Cancer Hospital, Clinical Oncology School of Fujian Medical University, No. 420 Fuma Road, Fuzhou, 350014, Fujian, China.
Yahan ZhengDepartment of Radiation Oncology, Fujian Cancer Hospital, Clinical Oncology School of Fujian Medical University, No. 420 Fuma Road, Fuzhou, 350014, Fujian, China.
Sisi YuDepartment of Radiation Oncology, Fujian Cancer Hospital, Clinical Oncology School of Fujian Medical University, No. 420 Fuma Road, Fuzhou, 350014, Fujian, China.
Jiali HuangDepartment of Radiation Oncology, Fujian Cancer Hospital, Clinical Oncology School of Fujian Medical University, No. 420 Fuma Road, Fuzhou, 350014, Fujian, China.
Jianji PanDepartment of Radiation Oncology, Fujian Cancer Hospital, Clinical Oncology School of Fujian Medical University, No. 420 Fuma Road, Fuzhou, 350014, Fujian, China.
Shaojun LinDepartment of Radiation Oncology, Fujian Cancer Hospital, Clinical Oncology School of Fujian Medical University, No. 420 Fuma Road, Fuzhou, 350014, Fujian, China.
Qiaojuan GuoDepartment of Radiation Oncology, Fujian Cancer Hospital, Clinical Oncology School of Fujian Medical University, No. 420 Fuma Road, Fuzhou, 350014, Fujian, China. guoqiaojuan@163.com.
Yun XuDepartment of Radiation Oncology, Fujian Cancer Hospital, Clinical Oncology School of Fujian Medical University, No. 420 Fuma Road, Fuzhou, 350014, Fujian, China. 308466040@qq.com.

Funding

Fujian Provincial Health Technology Project 2021QNA040Fujian Provincial Natural Science Foundation of China 2023J011271Fujian Provincial Natural Science Foundation of China 2024J011077Grant from the Joint Funds for the innovation of science and Technology, Fujian province 2023Y9208Startup Fund for scientific research, Fujian Medical University 2022QH1153
6 · The paper itself

Abstract

Larynx cancer poses a significant public health challenge in China, with rising incidence and mortality rates over the past decades. Understanding the long-term trends and underlying factors is crucial for effective intervention and policy formulation. Data were utilized from the global burden of disease (GBD) Study 2021 to analyze the incidence, prevalence, mortality, disability-adjusted life years (DALYs), years lived with disability (YLDs), and years of life lost (YLLs) due to larynx cancer in China from 1990 to 2021. Joinpoint regression analysis identified key changes in trends, while age-period-cohort (APC) analysis and decomposition analysis quantified the contributions of aging, epidemiological changes, and population growth to these trends. Our study found a significant increase in the incidence and prevalence of larynx cancer in China, particularly among males. The age-standardized incidence rate (ASIR) and age-standardized mortality rate (ASMR) for males were substantially higher than those for females. Decomposition analysis revealed that aging was the primary driver of increasing incidence and mortality rates, while epidemiological changes had a mitigating effect. Joinpoint analysis identified periods of rapid urbanization and economic growth as key turning points for increased incidence. Bayesian APC models projected a continued upward trend in incidence rates up to 2030. The rising burden of larynx cancer in China underscores the need for targeted public health interventions, including smoking cessation programs, environmental pollution control, and early detection strategies. Addressing gender disparities and implementing effective prevention measures are crucial to mitigating the impact of larynx cancer in China.

Indexed as

Global Burden of DiseaseLaryngeal NeoplasmsAdolescentAdultAgedAged, 80 and overBayes TheoremChinaDisability-Adjusted Life YearsFemaleForecastingHumansIncidenceMaleMiddle AgedPrevalenceAgingBayesian age-period-cohort analysisChinaDisease burdenEpidemiological changesGender disparitiesIncidenceLarynx cancerMortalityPrevalence

Identifiers

PMID39489769
PMCPMC11532332

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.