Evidence map›Paper›PMID 39489179›Full record

ReviewJournal of hepatology2025

Is there a safe limit for consumption of alcohol?

Jessica Ann Musto, Randall Brown, Michael Ronan Lucey

Abstract readReview
In one paragraph

Review in Journal of hepatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jessica Ann MustoDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Randall BrownDepartment of Family Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Michael Ronan LuceyDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA. Electronic address: mrl@medicine.wisc.edu.

Funding

Data Driven Strategies for Substance Misuse Identification in Hospitalized PatientsR01DA051464 · NIDA · UNIVERSITY OF WISCONSIN-MADISON · PI Majid Afshar · 2020 to 2026
$4.5M
Integrating mHealth for Alcohol Use Disorders into Clinical PracticeR01AA024150 · NIAAA · UNIVERSITY OF WISCONSIN-MADISON · PI QUANBECK, ANDREW · 2018 to 2022
$3.3M
1/4-American Consortium of Early Liver Transplantation-Prospective Alcohol-associated liver disease Cohort Evaluation (ACCELERATE-PACE)R01AA030960 · NIAAA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Norah A. Terrault · 2023 to 2026
$2.3M
3/4-American Consortium of Early Liver Transplantation-Prospective Alcohol-associated liver disease Cohort Evaluation (ACCELERATE-PACE)R01AA030966 · NIAAA · UNIVERSITY OF WISCONSIN-MADISON · PI Michael Ronan Lucey · 2023 to 2026
$1.6M
The Addiction Health Services Research (ASHR) conferenceR13DA058506 · NIDA · UNIVERSITY OF WISCONSIN-MADISON · PI Randall T Brown, Andrew Quanbeck · 2023 to 2026
$80k
NIAAA NIH HHS R01 AA024150NIAAA NIH HHS R01 AA030960NIAAA NIH HHS R01 AA030966NIDA NIH HHS R01 DA051464NIDA NIH HHS R13 DA058506
6 · The paper itself

Abstract

In order to understand and curb the harms related to alcohol, it will be necessary to think beyond patterns of use that meet criteria for a diagnosis of alcohol use disorder or addiction. Current research suggests that regular daily alcohol use does not confer a health benefit, and, for many persons, even relatively low consumption is associated with a health risk. Determining a safe limit for alcohol consumption is challenging both for the individual person and for society. We conclude that excessive drinking is always risky. We provide a list of circumstances, such as chronic illness, driving a vehicle, or pregnancy where persons should be advised to abstain from alcohol. We recognise the need to encourage less consumption of alcohol, particularly in young adults and older adults with co-morbid conditions (especially if taking multiple medications). Finally, we offer the modest proposal that, for persons without the contributing negative influences described above, consumption which adheres to one drink per session, with interspersed abstinent days, does not constitute a meaningful risk to health.

Indexed as

Alcohol DrinkingAdultAlcoholismFemaleHumansPregnancyabstinenceAlcohol use disorderdrinking

Identifiers

PMID39489179
PMCPMC11830546

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.