Evidence map›Paper›PMID 39488699›Full record

ArticleJournal of nanobiotechnology2024

Magnetic 3D macroporous MOF oriented urinary exosome metabolomics for early diagnosis of bladder cancer.

Yiqing Cao, Jianan Feng, Qiao Zhang, Chunhui Deng, Chen Yang, Yan Li

Abstract read
In one paragraph

Article in Journal of nanobiotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yiqing CaoCenter for Medical Research and Innovation, Shanghai Pudong Hospital & Depatment of Pharmaceutical Analysis, School of Pharmacy, Fudan University, Shanghai, 201203, China.
Jianan FengSchool of Pharmacy, Shanghai University of Medicine and Health Sciences, Shanghai, 201318, China.
Qiao ZhangCenter for Instrument Analysis, School of Pharmacy, Fudan University, Shanghai, 201203, China.
Chunhui DengDepartment of Chemistry, Institutes of Biomedical Sciences, Fudan University, Shanghai, 200032, China. chdeng@fudan.edu.cn.
Chen YangDepartment of Urology, Huashan Hospital, Fudan University, Shanghai, 200040, China. YangC_huashan@163.com.
Yan LiCenter for Medical Research and Innovation, Shanghai Pudong Hospital & Depatment of Pharmaceutical Analysis, School of Pharmacy, Fudan University, Shanghai, 201203, China. yanli@fudan.edu.cn.

Funding

National Natural Science Foundation of China no. 22274025 and 21974024
6 · The paper itself

Abstract

Bladder cancer (BCa) exhibits the escalating incidence and mortality due to the untimely and inaccurate early diagnosis. Urinary exosome metabolites, carrying critical tumor cell information and directly related to bladder, emerge as promising non-invasive diagnostic biomarkers of BCa. Herein, the magnetic 3D ordered macroporous zeolitic imidazolate framework-8 (magMZIF-8) is synthesized and used for efficient urinary exosome isolation. Notably, beyond retaining the single crystals and micropores of conventional ZIF-8, MZIF-8 is further enhanced with highly oriented and ordered macropores (150 nm) and the large specific surface area (973 m

Indexed as

Early Detection of CancerExosomesMetabolomicsMetal-Organic FrameworksUrinary Bladder NeoplasmsAgedBiomarkers, TumorFemaleHumansMaleMiddle AgedPorosityTandem Mass SpectrometryZeolitesBiomarkers, TumorMetal-Organic FrameworksZeolitesBladder cancerExosomeMass spectrometryMetabolomicsMOF

Identifiers

PMID39488699
PMCPMC11531116

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.