Evidence map›Paper›PMID 39488652›Full record

ArticleNPJ digital medicine2024

Predicting deterioration in dengue using a low cost wearable for continuous clinical monitoring.

Damien Keng Ming, John Daniels, Ho Quang Chanh, Stefan Karolcik, Bernard Hernandez, Vasileios Manginas, Van Hao Nguyen, Quang Huy Nguyen, Tu Qui Phan, Thi Hue Tai Luong and 6 more

Abstract read
In one paragraph

Article in NPJ digital medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Damien Keng MingCentre for Antimicrobial Optimisation, Imperial College London, London, UK. d.ming@imperial.ac.uk.ORCID http://orcid.org/0000-0003-3125-6378
John DanielsCentre for Bio-Inspired Technology, Imperial College London, London, UK.ORCID http://orcid.org/0000-0002-4464-2625
Ho Quang ChanhOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.ORCID http://orcid.org/0000-0002-1840-0868
Stefan KarolcikCentre for Bio-Inspired Technology, Imperial College London, London, UK.ORCID http://orcid.org/0000-0002-3638-0741
Bernard HernandezCentre for Antimicrobial Optimisation, Imperial College London, London, UK.ORCID http://orcid.org/0000-0003-1010-3559
Vasileios ManginasCentre for Bio-Inspired Technology, Imperial College London, London, UK.ORCID http://orcid.org/0009-0006-9145-9328
Van Hao NguyenHospital for Tropical Diseases, Ho Chi Minh City, Vietnam.
Quang Huy NguyenOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Tu Qui PhanHospital for Tropical Diseases, Ho Chi Minh City, Vietnam.
Thi Hue Tai LuongHospital for Tropical Diseases, Ho Chi Minh City, Vietnam.
Huynh Trung TrieuHospital for Tropical Diseases, Ho Chi Minh City, Vietnam.ORCID http://orcid.org/0000-0003-4922-6548
Alison Helen HolmesCentre for Antimicrobial Optimisation, Imperial College London, London, UK.ORCID http://orcid.org/0000-0001-5554-5743
Vinh Tho PhanHospital for Tropical Diseases, Ho Chi Minh City, Vietnam.
Pantelis GeorgiouCentre for Antimicrobial Optimisation, Imperial College London, London, UK.ORCID http://orcid.org/0000-0003-2476-3857
Sophie YacoubOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.ORCID http://orcid.org/0000-0002-2910-7819
VITAL consortium

Funding

Wellcome Trust
6 · The paper itself

Abstract

Close vital signs monitoring is crucial for the clinical management of patients with dengue. We investigated performance of a non-invasive wearable utilising photoplethysmography (PPG), to provide real-time risk prediction in hospitalised individuals. We performed a prospective observational clinical study in Vietnam between January 2020 and October 2022: 153 patients were included in analyses, providing 1353 h of PPG data. Using a multi-modal transformer approach, 10-min PPG waveform segments and basic clinical data (age, sex, clinical features on admission) were used as features to continuously forecast clinical state 2 h ahead. Prediction of low-risk states (17,939/80,843; 22.1%), defined by NEWS2 and mSOFA < 6, was associated with an area under the precision-recall curve of 0.67 and an area under the receiver operator curve of 0.83. Implementation of such interventions could provide cost-effective triage and clinical care in dengue, offering opportunities for safe ambulatory patient management.

Identifiers

PMID39488652
PMCPMC11531560

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.