ArticleNPJ precision oncology2024
Remission rate, toxicity and pharmacokinetics of venetoclax-based induction regimens in untreated pediatric acute myeloid leukemia.
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Article in NPJ precision oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9citing papers in PubMed
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Who cites it
9 citing papers in PubMed.
- Isavuconazole as primary antifungal prophylaxis in pediatric hematological patients: a clinical and pharmacokinetic analysis.Antimicrobial agents and chemotherapy · 2026Article
- Association between venetoclax concentration and febrile neutropenia in acute leukemia: a retrospective analysis.European journal of clinical pharmacology · 2026Article
- A perfused, parallelized blood brain barrier-tumor platform for compound permeation and efficacy investigations.Microsystems & nanoengineering · 2026Article
- Neutropenia and infectious events during off-label treatment with venetoclax in children with malignant disease: a pharmacovigilance analysis of FDA adverse event reporting system reports.Annals of hematology · 2026Article
- [Evolving treatment landscape of pediatric acute leukemia: integration and breakthroughs in immunotherapy and targeted therapy].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026Review
- Advances in Targeting Growth Factor Signalling in Neuroblastoma and Overcoming Drug Resistance.Cells · 2025Review
- Exploring Novel Applications: Repositioning Clinically Approved Therapies for Medulloblastoma Treatment.Cancers · 2025Article
- Cancer-associated fibroblasts in hepatocellular carcinoma: heterogeneity, mechanisms and therapeutic targets.Hepatology international · 2025Review
- Exposure-response analyses of venetoclax combined with hypomethylating agents in myelodysplastic syndromes: a retrospective study.Frontiers in pharmacology · 2025Article
Corrections and comments
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Authors and funding
21 authors.
Xiaojia Wen *Leukemia Department, Hematology Center, Beijing Key Laboratory of Pediatric Hematology Oncology; National Key Clinical Discipline of Pediatric Hematology, National Key Discipline of Pediatrics (Capital Medical University); Key Laboratory of Major Diseases in Children, Ministry of Education; Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, 56 Nanlishi Road, Beijing, China.
Yu Lu *Hematology Oncology Center, Baoding Key Laboratory of Precision Medicine for Pediatric Hematology Oncology; Baoding Hospital of Beijing Children's Hospital, Capital Medical University, National Center for Children's Health in Baoding, Beijing, China.
Yanming LiDepartment of pharmacy, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, 56 Nanlishi Road, Beijing, China.
Peijing QiLeukemia Department, Hematology Center, Beijing Key Laboratory of Pediatric Hematology Oncology; National Key Clinical Discipline of Pediatric Hematology, National Key Discipline of Pediatrics (Capital Medical University); Key Laboratory of Major Diseases in Children, Ministry of Education; Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, 56 Nanlishi Road, Beijing, China.
Ying WuLeukemia Department, Hematology Center, Beijing Key Laboratory of Pediatric Hematology Oncology; National Key Clinical Discipline of Pediatric Hematology, National Key Discipline of Pediatrics (Capital Medical University); Key Laboratory of Major Diseases in Children, Ministry of Education; Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, 56 Nanlishi Road, Beijing, China.
Jiaole YuLeukemia Department, Hematology Center, Beijing Key Laboratory of Pediatric Hematology Oncology; National Key Clinical Discipline of Pediatric Hematology, National Key Discipline of Pediatrics (Capital Medical University); Key Laboratory of Major Diseases in Children, Ministry of Education; Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, 56 Nanlishi Road, Beijing, China.
Ruidong ZhangLeukemia Department, Hematology Center, Beijing Key Laboratory of Pediatric Hematology Oncology; National Key Clinical Discipline of Pediatric Hematology, National Key Discipline of Pediatrics (Capital Medical University); Key Laboratory of Major Diseases in Children, Ministry of Education; Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, 56 Nanlishi Road, Beijing, China.
Qian HuangHematology Oncology Center, Baoding Key Laboratory of Precision Medicine for Pediatric Hematology Oncology; Baoding Hospital of Beijing Children's Hospital, Capital Medical University, National Center for Children's Health in Baoding, Beijing, China.
Pengli HuangLeukemia Department, Hematology Center, Beijing Key Laboratory of Pediatric Hematology Oncology; National Key Clinical Discipline of Pediatric Hematology, National Key Discipline of Pediatrics (Capital Medical University); Key Laboratory of Major Diseases in Children, Ministry of Education; Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, 56 Nanlishi Road, Beijing, China.
Bei HouLeukemia Department, Hematology Center, Beijing Key Laboratory of Pediatric Hematology Oncology; National Key Clinical Discipline of Pediatric Hematology, National Key Discipline of Pediatrics (Capital Medical University); Key Laboratory of Major Diseases in Children, Ministry of Education; Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, 56 Nanlishi Road, Beijing, China.
Jie YangLeukemia Department, Hematology Center, Beijing Key Laboratory of Pediatric Hematology Oncology; National Key Clinical Discipline of Pediatric Hematology, National Key Discipline of Pediatrics (Capital Medical University); Key Laboratory of Major Diseases in Children, Ministry of Education; Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, 56 Nanlishi Road, Beijing, China.
Mengjia LiuLeukemia Department, Hematology Center, Beijing Key Laboratory of Pediatric Hematology Oncology; National Key Clinical Discipline of Pediatric Hematology, National Key Discipline of Pediatrics (Capital Medical University); Key Laboratory of Major Diseases in Children, Ministry of Education; Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, 56 Nanlishi Road, Beijing, China.
Huiqing LiuLeukemia Department, Hematology Center, Beijing Key Laboratory of Pediatric Hematology Oncology; National Key Clinical Discipline of Pediatric Hematology, National Key Discipline of Pediatrics (Capital Medical University); Key Laboratory of Major Diseases in Children, Ministry of Education; Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, 56 Nanlishi Road, Beijing, China.
Hongqiao LiHematology Oncology Center, Baoding Key Laboratory of Precision Medicine for Pediatric Hematology Oncology; Baoding Hospital of Beijing Children's Hospital, Capital Medical University, National Center for Children's Health in Baoding, Beijing, China.
Ning SunDepartment of pharmacy, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, 56 Nanlishi Road, Beijing, China.
Yanni ZhangDepartment of pharmacy, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, 56 Nanlishi Road, Beijing, China.
Yuanyuan ZhangLeukemia Department, Hematology Center, Beijing Key Laboratory of Pediatric Hematology Oncology; National Key Clinical Discipline of Pediatric Hematology, National Key Discipline of Pediatrics (Capital Medical University); Key Laboratory of Major Diseases in Children, Ministry of Education; Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, 56 Nanlishi Road, Beijing, China.
Wei LinLeukemia Department, Hematology Center, Beijing Key Laboratory of Pediatric Hematology Oncology; National Key Clinical Discipline of Pediatric Hematology, National Key Discipline of Pediatrics (Capital Medical University); Key Laboratory of Major Diseases in Children, Ministry of Education; Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, 56 Nanlishi Road, Beijing, China.
Jia FanLeukemia Department, Hematology Center, Beijing Key Laboratory of Pediatric Hematology Oncology; National Key Clinical Discipline of Pediatric Hematology, National Key Discipline of Pediatrics (Capital Medical University); Key Laboratory of Major Diseases in Children, Ministry of Education; Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, 56 Nanlishi Road, Beijing, China.
Yan LiuHematology Oncology Center, Baoding Key Laboratory of Precision Medicine for Pediatric Hematology Oncology; Baoding Hospital of Beijing Children's Hospital, Capital Medical University, National Center for Children's Health in Baoding, Beijing, China. 1516420424@qq.com.
Huyong ZhengLeukemia Department, Hematology Center, Beijing Key Laboratory of Pediatric Hematology Oncology; National Key Clinical Discipline of Pediatric Hematology, National Key Discipline of Pediatrics (Capital Medical University); Key Laboratory of Major Diseases in Children, Ministry of Education; Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, 56 Nanlishi Road, Beijing, China. zhenghuyong@bch.com.cn.
Funding
National Natural Science Foundation of China (National Science Foundation of China) 82070154Natural Science Foundation of Beijing Municipality (Beijing Natural Science Foundation) 7222056
Abstract
The efficacy and safety of venetoclax in newly diagnosed pediatric acute myeloid leukemia (AML) are not well-established as they are in adults. Children newly diagnosed with AML were recommended for induction therapy with venetoclax and chemotherapy or hypomethylating agents (HMAs) as per for the ChiCTR1900027146 trial. Venetoclax was administered at a consistent dose of 200 mg/m
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