Evidence map›Paper›PMID 39488551›Full record

ArticleScientific reports2024

In-vitro and In-silico evaluation of antimicrobial and antibiofilm effect of Neem oil and Calcium hydroxide nanoparticles against Mutans Streptococci and Enterococcus faecalis isolated from endodontic infections.

Wedad M Nageeb, Sherouk Hussein Adam, Nasr Hashem, Nelly Abdelsalam

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. A comprehensive review ofBiochemistry and biophysics reports · 2026
    Review
  3. Evaluating Pharmacokinetics and Toxicity of Potential Therapeutics Against Enterococcus faecalis in Endodontic Pathologies.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Article
  4. Review
  5. Article
  6. 3 Biotech · 2025
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wedad M NageebDepartment of Medical Microbiology and Immunology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt. wedad_saleh@med.suez.edu.eg.
Sherouk Hussein AdamDepartment of Endodontics, Faculty of Dentistry, Suez Canal University, Ismailia, Egypt.
Nasr HashemDepartment of Endodontics, Faculty of Dentistry, Suez Canal University, Ismailia, Egypt.
Nelly AbdelsalamDepartment of Endodontics, Faculty of Dentistry, Suez Canal University, Ismailia, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Different Streptococcal species including Streptococcus mutans, Streptococcus sobrinus and Enterococcus faecalis are commonly isolated in root canal infections including refractory, recurrent, and persistent cases. Calcium hydroxide (Ca (OH)

Indexed as

Anti-Bacterial AgentsBiofilmsCalcium HydroxideEnterococcus faecalisNanoparticlesStreptococcus mutansComputer SimulationHumansMicrobial Sensitivity TestsMolecular Docking SimulationTerpenesAnti-Bacterial AgentsCalcium HydroxideTerpenesAntibiofilm effectCalcium hydroxideEndodontic medicationsNanoparticlesNeem antibacterialStreptococcus mutansStreptococcus sobrinus

Identifiers

PMID39488551
PMCPMC11531576

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.