Evidence map›Paper›PMID 39488422›Full record

SynthesisBMJ open2024

Breast cancer and its determinants in Ethiopia: a systematic review and meta-analysis.

Adisu Tafari Shama, Dufera Rikitu Terefa, Adisu Ewunetu Desisa, Matiyos Lema, Melese Chego Cheme, Edosa Tesfaye Geta, Jira Wakoya Feyisa, Bikila Regassa Feyisa, Bayise Biru

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Adisu Tafari ShamaDepartment of Public Health, Institute of Health Sciences, Wollega University, Nekemte, Ethiopia adisuteferi1906@gmail.com.ORCID 0000-0002-8963-9390
Dufera Rikitu TerefaDepartment of Public Health, Institute of Health Sciences, Wollega University, Nekemte, Ethiopia.ORCID 0000-0002-7064-7163
Adisu Ewunetu DesisaDepartment of Public Health, Institute of Health Sciences, Wollega University, Nekemte, Ethiopia.ORCID 0000-0003-4465-6629
Matiyos LemaDepartment of Public Health, Institute of Health Sciences, Wollega University, Nekemte, Ethiopia.ORCID 0000-0002-6411-4571
Melese Chego ChemeDepartment of Public Health, Institute of Health Sciences, Wollega University, Nekemte, Ethiopia.ORCID 0000-0002-0237-4028
Edosa Tesfaye GetaDepartment of Public Health, Institute of Health Sciences, Wollega University, Nekemte, Ethiopia.ORCID 0000-0002-7050-6846
Jira Wakoya FeyisaDepartment of Public Health, Institute of Health Sciences, Wollega University, Nekemte, Ethiopia.ORCID 0000-0002-9774-2398
Bikila Regassa FeyisaDepartment of Public Health, Institute of Health Sciences, Wollega University, Nekemte, Ethiopia.ORCID 0000-0002-7191-0218
Bayise BiruDepartment of Public Health, Institute of Health Sciences, Wollega University, Nekemte, Ethiopia.ORCID 0000-0003-0149-9379

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesBreast cancer is the leading cause of cancer morbidity and mortality among women. Still, there is a paucity of studies to know the magnitude of the problem in Ethiopia. Hence, this review was intended to pool the prevalence and identify the determinants of breast cancer in Ethiopia.

designA systematic review and meta-analysis was conducted. DATA SOURCES: Databases like PubMed/MEDLINE, HINARI, Science Direct, and Google Scholar, as well as websites of organisationsI organizations,rewere searched between 25 February and 6 March 2023. ELIGIBILITY CRITERIA: All observational studies in Ethiopia that reported either the magnitude and/or determinants of breast cancer regardless of publication status were included. DATA EXTRACTION AND SYNTHESIS: Two authors independently assessed and extracted the data. The Joanna Briggs Institute meta-analysis of statistics assessment and review instrument quality appraisal tool was used to assess the quality of the articles. Effect estimates were done by using the random-effects model. The meta-analysis results were displayed by using forest plots.

resultsSeventeen articles were reviewed with 24 435 total participants. The pooled proportion of breast cancer morbidity among patients with cancer was 20. 58% (95% CI 17.25%, 23.90%) in Ethiopia. Consuming packed foods (POR=2.12, 95% CI 1.41, 3.17), presence of high cholesterol (POR=4.08; 95% CI 2.75, 6.07), physical inactivity (POR=3.27; 95% CI 1.80, 5.94), high body mass index (BMI) (POR=2.27; 95% CI 0.85, 6.03), postmenopause (POR=2.25; 95% CI 1.63, 3.10), family history of cancer (POR=3.65; 95% CI 0.85, 15.71) and lack of breastfeeding (POR=2.76; 95% CI 0.90, 7.92) were the determinants of breast cancer.

conclusionsOne of five patients with cancer is diagnosed with breast cancer in Ethiopia. Furthermore, more than a quarter of women with cancer suffer from breast cancer. Processed food consumption, high cholesterol in the body, lack of physical activity, high BMI, postmenopause, family history of cancer and lack of breastfeeding were the risk factors for breast cancer. The use of healthy food sources such as fruits and vegetables, and homegrown varieties of crops rather than seeking processed foods would help. PROSPERO REGISTRATION NUMBER: CRD42023417733.

Indexed as

Breast NeoplasmsEthiopiaFemaleHumansPrevalenceRisk FactorsChronic DiseasePrimary Health CarePUBLIC HEALTHRisk Factors

Identifiers

PMID39488422
PMCPMC11535668

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.