Evidence map›Paper›PMID 39487221›Full record

ArticleSpinal cord2025

The effect of abdominal functional electrical stimulation on blood pressure in people with high level spinal cord injury.

Teodora Bojanic, Euan J McCaughey, Harrison T Finn, Peter Humburg, Rachel A McBain, Bonsan B Lee, Simon C Gandevia, Claire L Boswell-Ruys, Jane E Butler

Abstract read
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In one paragraph

Article in Spinal cord, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Teodora BojanicSpinal Cord Injury Research Centre, Neuroscience Research Australia, Randwick, NSW, 2031, Australia.
Euan J McCaugheySpinal Cord Injury Research Centre, Neuroscience Research Australia, Randwick, NSW, 2031, Australia.
Harrison T FinnSpinal Cord Injury Research Centre, Neuroscience Research Australia, Randwick, NSW, 2031, Australia.
Peter HumburgSpinal Cord Injury Research Centre, Neuroscience Research Australia, Randwick, NSW, 2031, Australia.
Rachel A McBainSpinal Cord Injury Research Centre, Neuroscience Research Australia, Randwick, NSW, 2031, Australia.
Bonsan B LeeSpinal Cord Injury Research Centre, Neuroscience Research Australia, Randwick, NSW, 2031, Australia.
Simon C GandeviaSpinal Cord Injury Research Centre, Neuroscience Research Australia, Randwick, NSW, 2031, Australia.ORCID 0000-0002-1345-3821
Claire L Boswell-Ruys *Spinal Cord Injury Research Centre, Neuroscience Research Australia, Randwick, NSW, 2031, Australia.ORCID 0000-0003-4922-5262
Jane E Butler *Spinal Cord Injury Research Centre, Neuroscience Research Australia, Randwick, NSW, 2031, Australia. j.butler@neura.edu.au.ORCID 0000-0002-5834-8152

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designSingle centre training study.

objectivesTo investigate, in a group of people with spinal cord injury (SCI), the effect of transcutaneous functional electrical stimulation of the abdominal muscles (abdominal FES) during cough training on blood pressure (BP), and how it is affected by injury characteristics and alters over time.

settingLaboratory and community.

methodsSixteen participants with SCI (C4-T5) underwent 25 of abdominal FES cough training (5 sets of 10 stimulated coughs) over 6 weeks as part of a previously published study on the effect of abdominal FES training on cough. Systolic BP (SBP), diastolic BP (DBP) and calculated mean arterial pressure (MAP) were measured at the completion of each set.

resultsAbdominal FES coughing resulted in an average ~30% acute increase in BP from initial resting BP across all sessions in almost all participants (p < 0.001). However, the increase in BP during abdominal FES coughs from rest reduced over the 25 sessions of training by ~35% for SBP, MAP and DBP (p = 0.024, p = 0.013 and p = 0.042, respectively). There was no meaningful change in resting BP over time (p = 0.935, p = 0.705 and p = 0.988, respectively). Overall, increases in BP during abdominal FES coughs were greatest for those with chronic injuries and cervical injuries.

conclusionsTranscutaneous abdominal FES during cough training acutely increases BP. However, the magnitude of the increase is reduced after 25 sessions of training. Abdominal FES may offer a solution to combat orthostatic hypotension, but its effectiveness may diminish over time.

Indexed as

Abdominal MusclesBlood PressureElectric Stimulation TherapySpinal Cord InjuriesTranscutaneous Electric Nerve StimulationAdultCoughFemaleHumansMaleMiddle AgedThoracic Vertebrae

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.