Evidence map›Paper›PMID 39487112›Full record

ArticleNature communications2024

Motorless transport of microtubules along tubulin, RanGTP, and salt gradients.

Suin Shim, Bernardo Gouveia, Beatrice Ramm, Venecia A Valdez, Sabine Petry, Howard A Stone

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Suin ShimDepartment of Mechanical and Aerospace Engineering, Princeton University, Princeton, NJ, USA. sshim@princeton.edu.ORCID 0000-0001-9128-8967
Bernardo GouveiaDepartment of Chemical and Biological Engineering, Princeton University, Princeton, NJ, USA.
Beatrice RammDepartment of Physics, Princeton University, Princeton, NJ, USA.ORCID 0000-0002-7402-1942
Venecia A ValdezDepartment of Molecular Biology, Princeton University, Princeton, NJ, USA.
Sabine PetryDepartment of Molecular Biology, Princeton University, Princeton, NJ, USA.ORCID 0000-0002-8537-9763
Howard A StoneDepartment of Mechanical and Aerospace Engineering, Princeton University, Princeton, NJ, USA. hastone@princeton.edu.ORCID 0000-0002-9670-0639

Funding

National Science Foundation (NSF) CBET-2127563National Science Foundation (NSF) PHY-1734030
6 · The paper itself

Abstract

Microtubules are dynamic filaments that assemble spindles for eukaryotic cell division. As the concentration profiles of soluble tubulin and regulatory proteins are non-uniform during spindle assembly, we asked if diffusiophoresis - motion of particles under solute gradients - can act as a motorless transport mechanism for microtubules. We identify the migration of stable microtubules along cytoplasmic and higher concentration gradients of soluble tubulin, MgCl

Indexed as

Microtubulesran GTP-Binding ProteinTubulinXenopus laevisAnimalsBiological TransportDiffusionran GTP-Binding ProteinTubulin

Identifiers

PMID39487112
PMCPMC11530526

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.