Evidence map›Paper›PMID 39487019›Full record

ReviewClinics in perinatology2024

Research on Maternal Vaccination for HIV Prevention.

Krithika P Karthigeyan, Christian Binuya, Kenneth Vuong, Sallie R Permar, Ashley N Nelson

Abstract readReview
In one paragraph

Review in Clinics in perinatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Krithika P KarthigeyanDepartment of Pediatrics, Weill Cornell Medicine, 413 East 69th Street, BB-869E, New York City, NY 10021, USA.
Christian BinuyaDepartment of Pediatrics, Weill Cornell Medicine, 413 East 69th Street, BB-869E, New York City, NY 10021, USA.
Kenneth VuongDepartment of Pediatrics, Weill Cornell Medicine, 413 East 69th Street, BB-869E, New York City, NY 10021, USA.
Sallie R PermarDepartment of Pediatrics, Weill Cornell Medicine, Drukier Institute for Children's Health, 413 East 69th Street, New York City, NY 10021, USA. Electronic address: sap4017@med.cornell.edu.
Ashley N NelsonDepartment of Pediatrics, Weill Cornell Medicine, Drukier Institute for Children's Health, 413 East 69th Street, New York City, NY 10021, USA. Electronic address: asn4002@med.cornell.edu.

Funding

Project 2: RNA vaccination in early life to induce potent and broad HIV Env-specific antibody responsesP01AI117915 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI DE PARIS, KRISTINA, PERMAR, SALLIE R. · 2015 to 2024
$21.2M
Escape of maternal plasma broadly neutralizing antibody as a mechanism of mother to child HIV transmissionR01AI162245 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI PERMAR, SALLIE R. · 2021 to 2024
$3.2M
NIAID NIH HHS P01 AI117915NIAID NIH HHS R01 AI162245
6 · The paper itself

Abstract

Despite increased uptake of antiretroviral therapy (ART) among pregnant people living with human immunodeficiency virus (HIV), vertical transmission remains the most important route of pediatric HIV acquisition. The numbers of HIV acquisitions in infancy have remained alarmingly stagnant in recent years. It is evident that additional strategies that can synergize with ART will be required to end the pediatric HIV epidemic. In this review, we discuss the potential for immune-based interventions that can be administered in conjunction with current ART-based strategies to the birthing parent for prevention of vertical transmission of HIV-1, and the potential challenges associated with each approach.

Indexed as

HIV InfectionsInfectious Disease Transmission, VerticalPregnancy Complications, InfectiousAIDS VaccinesAnti-HIV AgentsFemaleHIV-1HumansInfant, NewbornPregnancyVaccinationAIDS VaccinesAnti-HIV AgentsBroadly neutralizing antibodiesHuman immunodeficiency virus-1Passive immunization

Identifiers

PMID39487019
PMCPMC11531644

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.