Evidence map›Paper›PMID 39486857›Full record

Observational studyThe Journal of rheumatology2025

Disparities in Time to Diagnosis of Radiographic Axial Spondyloarthritis.

Renato Ferrandiz-Espadin, Gabriela Rabasa, Sarah Gasman, Brooke McGinley, Rachael Stovall, S Reza Jafarzadeh, Jean W Liew, Maureen Dubreuil

Abstract readObservational Study
In one paragraph

Observational study in The Journal of rheumatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Year in Review: Axial Spondyloarthritis.Mediterranean journal of rheumatology · 2026
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Renato Ferrandiz-EspadinR. Ferrandiz-Espadin, MD, MHA, Department of Internal Medicine, North Alabama Medical Center, Florence, Alabama.ORCID 0000-0001-6104-2712
Gabriela RabasaG. Rabasa, MS, J.W. Liew, MD, MS, Section of Rheumatology, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts.ORCID 0000-0002-4446-8129
Sarah GasmanS. Gasman, MSc, Department of Pediatrics, Boston Medical Center, Boston, Massachusetts.
Brooke McGinleyB. McGinley, BS, BA, S.R. Jafarzadeh, DVM, MPVM, PhD, School of Public Health, Boston University, Boston, Massachusetts.
Rachael StovallR. Stovall, MD, MAS, Division of Rheumatology, University of Washington, Seattle, Washington.ORCID 0000-0002-0355-4020
S Reza JafarzadehB. McGinley, BS, BA, S.R. Jafarzadeh, DVM, MPVM, PhD, School of Public Health, Boston University, Boston, Massachusetts.ORCID 0000-0002-1099-9175
Jean W LiewG. Rabasa, MS, J.W. Liew, MD, MS, Section of Rheumatology, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts.ORCID 0000-0002-8104-2450
Maureen DubreuilM. Dubreuil, MD, MSc, Section of Rheumatology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, and Division of Rheumatology, University of Washington, Seattle, Washington, USA. mdubreui@bu.edu.ORCID 0000-0002-6253-1515

Funding

Project-005UL1TR001430 · NCATS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BAIR-MERRITT, MEGAN H, CENTER, DAVID M. · 2015 to 2024
$52.3M
Research and Evaluation Support Core Unit (RESCU Core)P30AR072571 · NIAMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Michael Paul Lavalley · 2019 to 2026
$6.9M
BUSPH Interdisciplinary Training Program for BiostatisticiansT32GM140972 · NIGMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Kathryn L Lunetta, Laura Forsberg White · 2021 to 2026
$1.9M
NCATS NIH HHS UL1 TR001430NIAMS NIH HHS P30 AR072571NIGMS NIH HHS T32 GM140972
6 · The paper itself

Abstract

objectiveRadiographic axial spondyloarthritis (r-axSpA) has a 7-year average diagnostic delay. Although the effects of sex or gender on time to diagnosis have been evaluated, the role of social determinants of health remains understudied. We assessed whether time from initial clinical documentation of r-axSpA symptoms to r-axSpA diagnosis (diagnostic delay) varies based on sex, race, ethnicity, and/or the presence of social needs.

methodsWe studied patients with r-axSpA from a tertiary center from 2000 to 2022. The cohort was built with the Observational Health Data Sciences and Informatics (OHDSI) network. For the primary analysis, we assessed the time from back pain and/or spinal pain to r-axSpA diagnosis and, secondarily, the time to r-axSpA from any other r-axSpA-related condition. To estimate differences in diagnostic delay, we employed an accelerated failure time parametric survival model.

resultsWe included 404 patients (mean age 49 years; 38.6% female), with 25.5% identifying as Black, 31.1% as other or unknown race, and 14.1% as Hispanic. Patients with a documented social need had a 21% increase in time from back pain to r-axSpA diagnosis (95% CI 0.93-1.56). In patients with any r-axSpA-related condition, time to diagnosis similarly increased by 21% (95% CI 0.92-1.57). Considering that there is an average time to diagnosis of 34 months, a social need increased time to diagnosis by 7 months.

conclusionThis study reveals a trend toward diagnostic delay in r-axSpA related to social need, sex, race, and ethnicity. Future studies should focus on referral strategies to enable prompt diagnosis and optimize care.

Indexed as

Axial SpondyloarthritisDelayed DiagnosisHealthcare DisparitiesAdultBack PainFemaleHumansMaleMiddle AgedRadiographySex FactorsTime Factorsankylosing spondylitisepidemiologysocial disparitiesspondyloarthropathy

Identifiers

PMID39486857
PMCPMC11961325

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.