Evidence map›Paper›PMID 39486803›Full record

Trial reportBMJ open ophthalmology2024

Clinical outcomes and prognostic factors in patients with nasolacrimal duct obstruction or stenosis using dacryoendoscopy.

Hongxun Li, Jiagen Li, Lei Zhang, Lihong Yang, Yun Zhao, Hong Zhao, Ye Pan

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in BMJ open ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05999058 (Clinical Characteristics and Treatment Outcomes of Nasolacrimal Duct Obstruction Using Dacryoendoscopy), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05999058 nacompletednot on this map

Clinical Characteristics and Treatment Outcomes of Nasolacrimal Duct Obstruction Using Dacryoendoscopy

TypeinterventionalSponsorTianjin Eye HospitalRan2019 to 2023Enrolled522ConditionsLacrimal Duct ObstructionArmsDacryoendoscopic-assisted laser dacryoplasty with silicone intubation
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Outcomes of dacryocystorhinostomy with or without stent Insertion-A systematic review and Meta-analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hongxun LiDepartment of Orbital and Oculoplastic Surgery, Tianjin Eye Hospital, Tianjin, China.
Jiagen LiDepartment of Orbital and Oculoplastic Surgery, Tianjin Eye Hospital, Tianjin, China.
Lei ZhangDepartment of Orbital and Oculoplastic Surgery, Tianjin Eye Hospital, Tianjin, China.
Lihong YangDepartment of Orbital and Oculoplastic Surgery, Tianjin Eye Hospital, Tianjin, China.ORCID 0000-0003-2037-8214
Yun ZhaoDepartment of Orbital and Oculoplastic Surgery, Tianjin Eye Hospital, Tianjin, China.
Hong ZhaoDepartment of Orbital and Oculoplastic Surgery, Tianjin Eye Hospital, Tianjin, China.
Ye PanDepartment of Orbital and Oculoplastic Surgery, Tianjin Eye Hospital, Tianjin, China panye6521@163.com.ORCID 0000-0002-2964-1042

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the effectiveness of dacryoendoscopic-assisted laser dacryoplasty with silicone intubation (DLDI) for the management of nasolacrimal duct obstruction (NLDO) or stenosis, and to identify the factors associated with DLDI failure. METHODS AND ANALYSIS: This study was designed as a prospective, single-centre cohort study. Patients with NLDO or stenosis who underwent DLDI from December 2019 to December 2021 at Tianjin Eye Hospital were considered for enrolment. The Kaplan-Meier estimator was used to assess the anatomical and functional success rate of DLDI within 2 years follow-up after removal of the silicone stent. Cox proportional hazards regression models were used to identify risk factors for treatment failure.

results170, 174 and 178 eyes were included in Groups A (proximal NLDO), B (distal NLDO) and C (nasolacrimal duct stenosis), respectively. The overall anatomical success rate was 84.8% for the entire cohort at the 2-year follow-up. The cumulative anatomical or functional success rate for Groups B and C was significantly higher than that for Group A. In the multivariable model, a higher risk of failed DLDI surgery was associated with a history of chronic dacryocystitis (HR=3.07; p<0.001) and a longer duration of epiphora than 1 year (HR=2.67; p<0.001). Of the 522 eyes, 37 patients (7.1%) had surgery-related complications.

conclusionsDLDI is an effective minimally invasive technique for treatment in patients with distal NLDO or stenosis. Factors associated with a higher risk of reoperation include a longer duration of epiphora and a history of chronic dacryocystitis. TRIAL REGISTRATION NUMBER: NCT05999058.

Indexed as

DacryocystorhinostomyEndoscopyLacrimal Duct ObstructionNasolacrimal DuctAdultAgedFemaleFollow-Up StudiesHumansIntubationLaser TherapyMaleMiddle AgedPrognosisProspective StudiesStentsLacrimal drainageOrbitTreatment Surgery

Identifiers

PMID39486803
PMCPMC11529774

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.