Evidence map›Paper›PMID 39486684›Full record

Trial reportThe American journal of clinical nutrition2025

Adaptive changes in multiple aspects of emotion regulation in the offspring of pregnant persons receiving a diet-and-exercise intervention relative to usual pregnancy care: a randomized controlled trial.

John E Krzeczkowski, Neda Mortaji, Stephanie Atkinson, Louis A Schmidt, Ryan J Van Lieshout

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The American journal of clinical nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01689961 (Be Healthy in Pregnancy), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01689961 nacompletednot on this map

Be Healthy in Pregnancy (BHIP) With Nutrition and Exercise

TypeinterventionalSponsorMcMaster UniversityRan2012 to 2019Enrolled242ConditionsPregnancy Complications, Weight GainArmsStructured + monitored nutrition and exercise intervention
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

John E KrzeczkowskiDepartment of Health Sciences, Brock University, St. Catharines, ON, Canada. Electronic address: jkrzeczkowski@brocku.ca.
Neda MortajiDepartment of Psychology, Neuroscience & Behaviour, McMaster University, Hamilton, ON, Canada.
Stephanie AtkinsonDepartment of Pediatrics, McMaster University, Hamilton, ON, Canada.
Louis A SchmidtDepartment of Psychology, Neuroscience & Behaviour, McMaster University, Hamilton, ON, Canada.
Ryan J Van LieshoutDepartment of Psychiatry and Behavioral Neurosciences, McMaster University, Hamilton, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHuman studies examining the influence of prenatal diet and/or exercise interventions on offspring neurodevelopment are mixed. Interventions that include the provision of whole foods, nutritional counseling, address exercise behaviors, and that utilize multimethod assessments of offspring emotion regulation (ER) may better reveal the impact of these interventions on neurodevelopment.

objectivesTo explore whether the Be Healthy in Pregnancy (BHIP) prenatal diet-and-exercise intervention improves ER in 22-mo-old offspring.

methodsPregnant persons (>18 y, singleton pregnancy) were recruited between 12 and 17 wk gestation and randomly assigned to the intervention [high protein energy-controlled diet via the provision of cottage cheese, Greek yogurt, low-fat milk, individualized biweekly nutritional counseling, a controlled walking program, and usual pregnancy care (UPC)] or control (UPC alone) groups. ER in offspring [m

resultsChildren exposed to the BHIP intervention exhibited medium to large effect size reductions in pregnant person and partner reported externalizing [effect size ƞ

conclusionsThis intervention was associated with medium/large effect size improvements in offspring ER. Larger trials are needed to confirm the potential of these interventions on offspring neurodevelopment. TRIAL REGISTRATION NUMBER: This trial was registered at www. CLINICALTRIALS: gov as NCT01689961 (21 September, 2012).

Indexed as

Emotional RegulationExerciseAdultDietFemaleHumansInfantMalePregnancyPrenatal CareYoung Adultchildemotion regulationprenatal dietprenatal exerciserandomized controlled trial

Identifiers

PMID39486684
PMCPMC11747193

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.