Evidence map›Paper›PMID 39485886›Full record

SynthesisBJS open2024

Reported outcomes in studies of intermittent claudication - first step toward a core outcome set: systematic review.

Akam Shwan, Segun Lamidi, Calvin Chan, Elizabeth Daniels, Charlie Song-Smith, Lydia Hanna, Viknesh Sounderajah, John S M Houghton, Rob D Sayers

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BJS open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Akam ShwanDepartment of Cardiovascular Sciences, University of Leicester, Leicester, UK.
Segun LamidiDepartment of Cardiovascular Sciences, University of Leicester, Leicester, UK.
Calvin ChanDepartment of Surgery and Cancer, Imperial College London, London, UK.
Elizabeth DanielsDepartment of Surgery and Cancer, Imperial College London, London, UK.
Charlie Song-SmithUniversity College London Medical School, London, UK.
Lydia HannaDepartment of Surgery and Cancer, Imperial College London, London, UK.
Viknesh SounderajahDepartment of Surgery and Cancer, Imperial College London, London, UK.ORCID 0000-0002-4595-8402
John S M HoughtonDepartment of Cardiovascular Sciences, University of Leicester, Leicester, UK.ORCID 0000-0002-9159-5307
Rob D SayersDepartment of Cardiovascular Sciences, University of Leicester, Leicester, UK.

Funding

George Davies Charitable Trust 1024818
6 · The paper itself

Abstract

introductionThis review aimed to compile an exhaustive list of all outcome measures and identify different characteristics of the outcomes reported in studies of intermittent claudication as the first step in developing a core outcome set for intermittent claudication.

methodMedline and Embase were searched for all studies including individuals with intermittent claudication and reporting ≥1 outcome from January 2015 to August 2024. Abstract, full text screening and data extraction were performed by two investigators independently. All reported outcome measures were extracted verbatim and categorized by Dodd's domains (Core Outcome Measures in Effectiveness Trials registration: COMIC Study, 1590; https://www.comet-initiative.org/Studies/Details/1590).

results4985 studies were screened and 408 were included. A total of 541 unique outcomes across 25 Dodd's domains were identified. Ankle-brachial pressure index was the most frequently reported outcome. Among the 541 unique outcomes, 386 outcomes were only reported once. Only 38.9% of the studies exclusively included patients with intermittent claudication. Patient-reported outcomes were reported in 36.2% of studies. There were wide variations in the definition of commonly used outcome measures (for example, major adverse limb event and primary patency) across different studies.

conclusionThere is substantial heterogeneity in reported outcomes in studies of intermittent claudication. Most reported outcomes are clinical/physiology oriented rather than patient centred. Development of a core outcome set for intermittent claudication is vital to improve and standardize reporting in future research.

Indexed as

Intermittent ClaudicationPatient Reported Outcome MeasuresAnkle Brachial IndexHumansOutcome Assessment, Health Care

Identifiers

PMID39485886
PMCPMC11529788

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.