ArticleProceedings of the National Academy of Sciences of the United States of America2024
Structural duality enables a single protein to act as a toxin-antidote pair for meiotic drive.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Rapid protamine evolution suppresses meiotic drive inScience advances · 2026Article
- Alternatively spliced killer-protector system confers S19-mediated hybrid male sterility in rice.Nature communications · 2026Article
- Evolutionary persistence and divergence of thebioRxiv : the preprint server for biology · 2025Article
- Killer meiotic drive executed by two alternative conformations of a single protein.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- A meiotic driver hijacks an epigenetic reader to disrupt mitosis in noncarrier offspring.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
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Abstract
In sexual reproduction, selfish genetic elements known as killer meiotic drivers (KMDs) bias inheritance by eliminating gametes that do not carry them. The selective killing behavior of most KMDs can be explained by a toxin-antidote model, where a toxin harms all gametes while an antidote provides resistance to the toxin in carriers. This study investigates whether and how the KMD element
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