Evidence map›Paper›PMID 39485599›Full record

ArticleCell biochemistry and biophysics2025

In silico genome-wide analysis of the growth-regulating factor gene family and their expression profiling in Vitis vinifera under biotic stress.

Nimra Nazir, Azhar Iqbal, Hadia Hussain, Faisal Ali, Khalid S Almaary, Most Nazmin Aktar, Muhammad Sajid, Mohammed Bourhia, Ahmad Mohammad Salamatullah

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Article in Cell biochemistry and biophysics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Nimra NazirDepartment of Biotechnology, Faculty of Life Sciences, University of Okara, Okara, Punjab, 56300, Pakistan.
Azhar IqbalDepartment of Biotechnology, Faculty of Life Sciences, University of Okara, Okara, Punjab, 56300, Pakistan.
Hadia HussainDepartment of Biotechnology, Faculty of Life Sciences, University of Okara, Okara, Punjab, 56300, Pakistan.
Faisal AliDepartment of Biotechnology, Faculty of Life Sciences, University of Okara, Okara, Punjab, 56300, Pakistan.
Khalid S AlmaaryDepartment of Botany and Microbiology, College of Science, King Saud University, P. O. BOX 2455, Riyadh, 11451, Saudi Arabia. kalmary@ksu.edu.sa.
Most Nazmin AktarSchool of Natural Sciences, Macquarie University, Sydney, NSW 2109, Australia.
Muhammad SajidDepartment of Biotechnology, Faculty of Life Sciences, University of Okara, Okara, Punjab, 56300, Pakistan. sajid@uo.edu.pk.
Mohammed BourhiaLaboratory of Biotechnology and Natural Resources Valorization, Faculty of Sciences, Ibn Zohr University, 80060, Agadir, Morocco.
Ahmad Mohammad SalamatullahDepartment of Food Science & Nutrition, College of Food and Agricultural Sciences, King Saud University, 11 P.O. Box 2460, Riyadh, 11451, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growth regulatory factors (GRFs) are transcription factors that encode the proteins involved in plant growth and development. However, no comprehensive analysis of Vitis vinifera GRF genes has yet been conducted. In the current study, we performed a genome-wide analysis of the GRF gene family to explore the VvGRF gene's role in Vitis vinifera. We identified 30 VvGRF genes in the Vitis vinifera genome, localized over 20 chromosomes. Based on evolutionary analysis, 49 GRF genes (nine AtGRF, ten FvGRF, and 30 VvGRF) were clustered into six groups. Many cis-elements involved in light control, defense, and plant growth have been identified in the promoter region of VvGRF genes, and multiple miRNAs have been predicted to be involved in regulating VvGRF gene expression. Protein-protein interaction analysis showed that nine VvGRF proteins formed a complex protein interaction network. Furthermore, the gene expression analysis of VvGRF revealed that VvGRF-5 and VvGRF-6 were highly upregulated suggesting that these genes are involved in biotic responses. This study provides comprehensive insights into the functional characteristics and occurrence of the VvGRF gene family in Vitis vinifera, which may be applied in breeding programs to enhance the growth of Vitis vinifera varieties under stress and growth changes.

Indexed as

Gene Expression Regulation, PlantGenome, PlantMultigene FamilyPlant ProteinsStress, PhysiologicalTranscription FactorsVitisComputer SimulationGene Expression ProfilingMicroRNAsPhylogenyPromoter Regions, GeneticProtein Interaction MapsMicroRNAsPlant ProteinsTranscription FactorsExpression analysisGene structureGrowth regulatory factorPhylogenetic analysisVitis vinifera

Identifiers

PMID39485599

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