Evidence map›Paper›PMID 39485281›Full record

ArticleeLife2024

Calcineurin inhibition enhances

Priyanka Das, Alejandro Aballay, Jogender Singh

Abstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Iron-deplete diet enhancesbioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Priyanka DasDepartment of Biological Sciences, Indian Institute of Science Education and Research, Mohali, India.
Alejandro AballayDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, United States.ORCID https://orcid.org/0000-0002-5975-3352
Jogender SinghDepartment of Biological Sciences, Indian Institute of Science Education and Research, Mohali, India.ORCID https://orcid.org/0000-0002-7947-0405

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Council of Scientific and Industrial Research, India 37/1741/23/EMR-IIDepartment of Biotechnology, Ministry of Science and Technology, India BT/RLF/Re-entry/50/2020Department of Biotechnology, Ministry of Science and Technology, India HRD-17011/2/2023-HRD-DBTMinistry of Education, India MoE-STARS/STARS-2/2023-0116NIH HHS P40 OD010440Science and Engineering Research Board CRG/2023/001136Science and Engineering Research Board SRG/2020/000022
6 · The paper itself

Abstract

Calcineurin is a highly conserved calcium/calmodulin-dependent serine/threonine protein phosphatase with diverse functions. Inhibition of calcineurin is known to enhance the lifespan of

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsCalcineurinCaloric RestrictionDefecationLongevitySignal TransductionAnimalsBasic Helix-Loop-Helix ProteinsCalcineurin InhibitorsImmunity, InnateReceptors, Cytoplasmic and NuclearBasic Helix-Loop-Helix ProteinsCaenorhabditis elegans ProteinsCalcineurinCalcineurin InhibitorsHLH-30 protein, C elegansReceptors, Cytoplasmic and Nuclearcalorie restrictionC. eleganscell biologygeneticsgenomicshlh-30Intestinal bloatinglongevitynhr-8tax-6

Identifiers

PMID39485281
PMCPMC11530235

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.