Evidence map›Paper›PMID 39485055›Full record

ReviewJournal of cosmetic dermatology2025

Patchy Dermal Melanocytosis: Differential Diagnosis and Management.

Jiafang Zhu, Qingqing Cen, Rui Chang, Yue Han, Xiaoxi Lin

Abstract readReview
In one paragraph

Review in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiafang ZhuDepartment of Laser and Aesthetic Medicine, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID https://orcid.org/0000-0002-0805-5757
Qingqing CenDepartment of Laser and Aesthetic Medicine, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID https://orcid.org/0000-0003-2590-0147
Rui ChangDepartment of Laser and Aesthetic Medicine, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yue HanDepartment of Laser and Aesthetic Medicine, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID https://orcid.org/0000-0002-0645-0657
Xiaoxi LinDepartment of Laser and Aesthetic Medicine, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID https://orcid.org/0000-0002-7325-1367

Funding

Clinical Research Project of Shanghai Ninth People 's Hospital, Shanghai Jiao Tong University School of Medicine JYHX2022010Clinical Research Project of Shanghai Ninth People 's Hospital, Shanghai Jiao Tong University School of Medicine JYHX2024008National Natural Science Foundation of China 81971847National Natural Science Foundation of China 82272288Project of Biobank from Shanghai Ninth People 's Hospital, Shanghai Jiao Tong University School of Medicine YBKA202209Shandong Provincial Natural Science Foundation ZR2021QH291
6 · The paper itself

Abstract

backgroundNevus of Ito and Mongolian spots are distinct clinical presentations of patchy dermal melanocytosis, characterized by similar dermatological manifestations that can pose diagnostic difficulties for clinicians.

aimThis review aims to consolidate current understanding and research advancements on these conditions to facilitate clinical diagnosis, differential diagnosis, and management.

methodsA comprehensive search of databases including PubMed and Google Scholar was conducted, along with an analysis of pertinent literature retrieved from reference lists spanning nearly four decades.

resultsEpidemiological, clinical, and pathological profiles exhibit nuanced differences between the two conditions, with unique expressions under electron microscopy and the regression possibility. It is noteworthy that most Mongolian spots naturally fade with advancing age, in contrast to nevus of Ito, which persist and may potentially evolve into malignant lesions. While picosecond laser treatment has shown greater efficacy than nanosecond lasers, the lower-energy approach holds particular promise in pediatric cases. The therapeutic landscape for patchy dermal melanocytosis is evolving, shifting from selective photothermal action to photomechanical or subcellular photothermal modalities.

conclusionThis review underscores the importance of meticulous clinical assessment and the potential of innovative therapeutic approaches in managing these conditions.

Indexed as

Mongolian SpotNevus, PigmentedSkin NeoplasmsDiagnosis, DifferentialHumansLaser TherapyLow-Level Light TherapyMelanocytesSkindermal melanocytosislaser therapyMongolian spotnevus of Itopatchy melanocytosisphotomechanical effectphotothermal effect

Identifiers

PMID39485055
PMCPMC11743229

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.