Evidence map›Paper›PMID 39485029›Full record

ArticleCancer research communications2024

Spatial Context of Immune Checkpoints as Predictors of Overall Survival in Patients with Resectable Colorectal Cancer Independent of Standard Tumor-Node-Metastasis Stages.

Hao Kong, Qingxin Yang, Chunwei Wu, Xiangji Wu, Xinrui Yan, Li-Bin Huang, Lu Chen, Zong-Guang Zhou, Ping Wang, Hong Jiang

Abstract read
In one paragraph

Article in Cancer research communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Define a good prognosis ofFrontiers in oncology · 2025
    Article
  4. Terminally exhausted CD8Frontiers in immunology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hao Kong *Department of Pancreatic Surgery, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.ORCID 0000-0002-8683-5580
Qingxin Yang *Department of Pancreatic Surgery, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.ORCID 0000-0002-9685-6553
Chunwei Wu *Department of Pancreatic Surgery, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.ORCID 0009-0006-7194-0085
Xiangji WuDepartment of Pancreatic Surgery, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.ORCID 0009-0005-0526-8414
Xinrui YanDepartment of Pancreatic Surgery, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.ORCID 0009-0009-9870-8122
Li-Bin HuangLaboratory of Digestive Surgery, State Key Laboratory of Biotherapy, Sichuan University, Chengdu, China.ORCID 0000-0002-2614-5764
Lu ChenKey Laboratory of Birth Defects and Related Diseases of Women and Children of MOE, Department of Laboratory Medicine, State Key Laboratory of Biotherapy, West China Second University Hospital, Sichuan University, Chengdu, China.ORCID 0000-0002-1083-9729
Zong-Guang ZhouLaboratory of Digestive Surgery, State Key Laboratory of Biotherapy, Sichuan University, Chengdu, China.ORCID 0000-0002-7616-1199
Ping WangDepartment of Pancreatic Surgery, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.ORCID 0009-0009-4040-1144
Hong JiangDepartment of Pancreatic Surgery, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.ORCID 0000-0001-9481-9807

Funding

National Natural Science Foundation of China 82073158
6 · The paper itself

Abstract

significanceThe identification of specific spatial patterns of immune checkpoint expression that correlate with overall survival in patients with colon cancer suggests a potential prognostic tool for risk stratification and treatment selection. These findings pave the way for the development of novel therapeutic strategies to enhance antitumor immune responses.

Indexed as

Colorectal NeoplasmsAgedBiomarkers, TumorFemaleHumansImmune Checkpoint ProteinsLymphatic MetastasisMaleMiddle AgedNeoplasm StagingPrognosisBiomarkers, TumorImmune Checkpoint Proteins

Identifiers

PMID39485029
PMCPMC11589669

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.