Evidence map›Paper›PMID 39485000›Full record

ReviewAllergy2024

The influence of lifestyle and environmental factors on host resilience through a homeostatic skin microbiota: An EAACI Task Force Report.

Inge Kortekaas Krohn, Chris Callewaert, Hafsa Belasri, Britta De Pessemier, Celia Diez Lopez, Charlotte G Mortz, Liam O'Mahony, Marina Pérez-Gordo, Milena Sokolowska, Zsofia Unger and 3 more

Abstract readReview
In one paragraph

Review in Allergy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Nature prescription for patients with chronic respiratory diseases.The World Allergy Organization journal · 2026
    Review
  7. Review
  8. Article
  9. Observational
  10. Frontiers in cellular and infection microbiology · 2026
    Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Inge Kortekaas KrohnVrije Universiteit Brussel (VUB), Skin Immunology & Immune Tolerance (SKIN) Research Group, Brussels, Belgium.ORCID 0000-0003-3649-1131
Chris CallewaertFaculty of Bioscience Engineering, Ghent University, Centre for Microbial Ecology and Technology (CMET), Ghent, Belgium.ORCID 0000-0001-7697-9188
Hafsa BelasriVrije Universiteit Brussel (VUB), Skin Immunology & Immune Tolerance (SKIN) Research Group, Brussels, Belgium.ORCID 0009-0008-1642-1922
Britta De PessemierFaculty of Bioscience Engineering, Ghent University, Centre for Microbial Ecology and Technology (CMET), Ghent, Belgium.ORCID 0000-0002-3249-176X
Celia Diez LopezFaculty of Bioscience Engineering, Ghent University, Centre for Microbial Ecology and Technology (CMET), Ghent, Belgium.ORCID 0000-0001-8201-1157
Charlotte G MortzDepartment of Dermatology and Allergy Centre, Odense University Hospital, University of Southern Denmark, Odense, Denmark.ORCID 0000-0001-8710-0829
Liam O'MahonyAPC Microbiome Ireland, School of Microbiology, and Department of medicine, University College Cork, Cork, Ireland.ORCID 0000-0003-4705-3583
Marina Pérez-GordoDepartamento de Ciencias Médicas Básicas, Instituto de Medicina Molecular Aplicada (IMMA) Nemesio Díez, Facultad de Medicina, Universidad San Pablo-CEU, CEU Universities, Madrid, Spain.ORCID 0000-0003-2003-4841
Milena SokolowskaSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.ORCID 0000-0001-9710-6685
Zsofia UngerDepartment of Dermatology, University Hospital, Heinrich-Heine University, Duesseldorf, Germany.
Eva UntersmayrInstitute of Pathophysiology and Allergy Research, Centre of Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-1963-499X
Bernhard HomeyDepartment of Dermatology, University Hospital, Heinrich-Heine University, Duesseldorf, Germany.ORCID 0000-0002-5784-4146
Cristina Gomez-CasadoDepartment of Dermatology, University Hospital, Heinrich-Heine University, Duesseldorf, Germany.ORCID 0000-0002-7707-6367

Funding

European Academy of Allergy and Clinical Immunology
6 · The paper itself

Abstract

Human skin is colonized with skin microbiota that includes commensal bacteria, fungi, arthropods, archaea and viruses. The composition of the microbiota varies at different anatomical locations according to changes in body temperature, pH, humidity/hydration or sebum content. A homeostatic skin microbiota is crucial to maintain epithelial barrier functions, to protect from invading pathogens and to interact with the immune system. Therefore, maintaining homeostasis holds promise to be an achievable goal for microbiome-directed treatment strategies as well as a prophylactic strategy to prevent the development of skin diseases, as dysbiosis or disruption of homeostatic skin microbiota is associated with skin inflammation. A healthy skin microbiome is likely modulated by genetic as well as environmental and lifestyle factors. In this review, we aim to provide a complete overview of the lifestyle and environmental factors that can contribute to maintaining the skin microbiome healthy. Awareness of these factors could be the basis for a prophylactic strategy to prevent the development of skin diseases or to be used as a therapeutic approach.

Indexed as

HomeostasisLife StyleMicrobiotaSkinEnvironmentHumansSkin Diseasesenvironmenthomeostasislifestylemicrobiomeskin

Identifiers

PMID39485000
PMCPMC11657040

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.