Evidence map›Paper›PMID 39484873›Full record

ArticlePediatrics2024

The Circumstances Surrounding Fatal Pediatric Opioid Poisonings, 2004-2020.

Julie R Gaither, Sarah McCollum, Kirsten Bechtel, John M Leventhal, Sasha Mintz

Abstract read
In one paragraph

Article in Pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julie R GaitherDepartment of Pediatrics, Yale School of Medicine, New Haven, Connecticut.
Sarah McCollumDepartment of Pediatrics, Yale School of Medicine, New Haven, Connecticut.
Kirsten BechtelDepartment of Pediatrics, Yale School of Medicine, New Haven, Connecticut.
John M LeventhalDepartment of Pediatrics, Yale School of Medicine, New Haven, Connecticut.
Sasha MintzNational Center for Fatality Review and Prevention, Michigan Public Health Institute, Okemos, Michigan.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
The Clinical Challenges and Costs of Caring for Infants with Neonatal Opioid Withdrawal Syndrome (NOWS) in the Post-Nursery PeriodK23HD109508 · NICHD · YALE UNIVERSITY · PI Julie Rozelle Gaither · 2023 to 2026
$669k
NCATS NIH HHS UL1 TR001863NICHD NIH HHS K23 HD109508
6 · The paper itself

Abstract

objectivesThere is little understanding of the circumstances behind fatal pediatric opioid poisonings. Our objective was to characterize opioid fatalities according to child, family, and household factors.

methodsWe used data from the National Fatality Review-Case Reporting System to describe the circumstances behind the deaths of children 0 to 17 years of age who died of an opioid poisoning (ie, prescription opioid, heroin, illicit fentanyl) between 2004 and 2020. Decedents were stratified into age groups: 0-4, 5-9, 10-14, and 15-17 years.

resultsThe majority (65.3%) of the 1696 fatal opioid poisonings occurred in the child's own home. Prescription opioids contributed to 91.8% of deaths, heroin contributed to 5.4%, and illicit fentanyl to 7.7%. Co-poisonings with nonopioid substances occurred in 43.2% of deaths. Among 0- to 4-year-olds, 33.9% died of homicide and 45.0% had a primary caregiver with a history of substance use/abuse. Among 10- to 14-year-olds and 15- to 17-year-olds, respectively, 42.0% and 72.8% of decedents had a history of substance use/abuse. In each age group, at least 25.0% of children were victims of previous child maltreatment.

conclusionsA history of maltreatment and substance use-whether on the part of the caregiver or the child-are common factors surrounding fatal pediatric opioid poisonings, the majority of which occur in the child's own home. Families with children of all ages would benefit from interventions focused on opioid prescribing, storage, disposal, and misuse. These findings also underscore the urgency of ensuring that access to naloxone becomes universal for families with a history of maltreatment and/or substance use.

Indexed as

Analgesics, OpioidAdolescentChildChild, PreschoolFemaleFentanylHeroinHumansInfantInfant, NewbornMaleOpiate OverdoseUnited StatesAnalgesics, OpioidFentanylHeroin

Identifiers

PMID39484873
PMCPMC11528886

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.