Evidence map›Paper›PMID 39484783›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2025

High Retention and Adherence With Rapid Long-acting Injectable Preexposure Prophylaxis Implementation in an Urban Safety Net Clinic Population.

Matthew A Spinelli, Ezra Bisom-Rapp, Megan J Heise, Christina Camp, Ayesha Appa, Albert Y Liu, Kevin Sassaman, Mary Shiels, Francis Mayorga-Munoz, Anthonia Chimezie and 3 more

Abstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Why is roll-out of long-acting PrEP agents so slow?Current opinion in HIV and AIDS · 2025
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Matthew A SpinelliDivision of HIV, ID, and Global Medicine, University of California, San Francisco, California, USA.ORCID 0000-0001-6368-8664
Ezra Bisom-RappDepartment of Medicine, University of California, San Francisco, California, USA.ORCID 0000-0003-1326-8922
Megan J HeiseDivision of HIV, ID, and Global Medicine, University of California, San Francisco, California, USA.ORCID 0000-0001-6651-2381
Christina CampDivision of HIV, ID, and Global Medicine, University of California, San Francisco, California, USA.ORCID 0000-0002-0592-7396
Ayesha AppaDivision of HIV, ID, and Global Medicine, University of California, San Francisco, California, USA.ORCID 0000-0002-4602-5954
Albert Y LiuSan Francisco Department of Public Health, Bridge HIV, San Francisco, California, USA.
Kevin SassamanDivision of HIV, ID, and Global Medicine, University of California, San Francisco, California, USA.
Mary ShielsDivision of HIV, ID, and Global Medicine, University of California, San Francisco, California, USA.
Francis Mayorga-MunozDivision of HIV, ID, and Global Medicine, University of California, San Francisco, California, USA.
Anthonia ChimezieDivision of HIV, ID, and Global Medicine, University of California, San Francisco, California, USA.
Janet NguyenDivision of HIV, ID, and Global Medicine, University of California, San Francisco, California, USA.ORCID 0009-0008-3446-888X
Jon OskarssonDivision of HIV, ID, and Global Medicine, University of California, San Francisco, California, USA.
Monica GandhiDivision of HIV, ID, and Global Medicine, University of California, San Francisco, California, USA.ORCID 0000-0002-7025-1994

Funding

Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVEN Grant DEEKS · 1988 to 2026
$93.6M
Training in HIV Translational ResearchT32AI060530 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Diane V Havlir · 2005 to 2026
$6.4M
Randomized Trial to Optimize Virologic Suppression Rates Using a Point-of-Care Urine Monitoring Assay (ROVING-PUMA)R01AI143340 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Monica Gandhi · 2018 to 2026
$5.6M
“Hair Lengthening”: Using Hair Levels to Interpret Long-Acting PrEP Studies.R37AI098472 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Monica Gandhi · 2023 to 2026
$3.2M
Unraveling the intersection of substance use, inflammation, and HIV via hair levelsR01DA059291 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Monica Gandhi, Pamina Mae Gorbach · 2023 to 2026
$3.0M
PrEP Point-of-Care Brief-Intervention for Adherence among Young Men Who Have Sex with Men (PrEP2-BAY Study)K23MH122286 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SPINELLI, MATTHEW A. · 2020 to 2024
$1.0M
NIAID NIH HHS 2R01AI143340NIAID NIH HHS P30 AI027763NIAID NIH HHS R01 AI143340NIAID NIH HHS R37 AI098472NIAID NIH HHS T32 AI060530NIDA NIH HHS R01 DA059291NIHNIMH NIH HHS K23 MH122286NIMH NIH HHS K23MH122286
6 · The paper itself

Abstract

In a low-barrier, long-acting preexposure prophylaxis (PrEP) program in a safety net setting, permitting same-day or next-day initiation, 85% of injections were on time, and 6-month retention was 83%, surpassing outcomes from most previously reported oral PrEP studies. With drop-in, wraparound services, similar retention among housing-insecure populations was seen. Long-acting PrEP expansion is urgently needed.

Indexed as

Anti-HIV AgentsHIV InfectionsMedication AdherencePre-Exposure ProphylaxisSafety-net ProvidersAdultFemaleHumansInjectionsMaleMiddle AgedUrban PopulationYoung AdultAnti-HIV Agentscabotegravirlow-barrierPrEPrapidretention

Identifiers

PMID39484783
PMCPMC12135906

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.