Evidence map›Paper›PMID 39484771›Full record

ReviewInfectious disorders drug targets2025

Mucormycosis and COVID-19: Unraveling the Interplay of Fungal Infection in a Global Health Crisis: An Overview.

Ali Moheb-Alian, Ali Akbari, Saghi Nooraei, Howra Bahrulolum, Zoheir Mohammadian Farsani, Negin Mokhtari, Mozhdeh Sadat Ebadi, Arezoo Mohammadian Farsani, Seyedmoein Khatami, Mohammadmahdi Esmaeili and 4 more

Abstract readReview
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In one paragraph

Review in Infectious disorders drug targets, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ali Moheb-AlianDepartment of Medical Biotechnology, National Institute for Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran.
Ali AkbariDepartment of System Biotechnology, National Institute for Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran.
Saghi NooraeiDepartment of System Biotechnology, National Institute for Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran.
Howra BahrulolumDepartment of System Biotechnology, National Institute for Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran.
Zoheir Mohammadian FarsaniDepartment of System Biotechnology, National Institute for Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran.
Negin MokhtariDepartment of System Biotechnology, National Institute for Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran.
Mozhdeh Sadat EbadiDepartment of System Biotechnology, National Institute for Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran.
Arezoo Mohammadian FarsaniDepartment of System Biotechnology, National Institute for Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran.
Seyedmoein KhatamiDepartment of System Biotechnology, National Institute for Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran.
Mohammadmahdi EsmaeiliDepartment of Biology, School of Natural Sciences, University of Padova, Padova, Italy.
Zahra KeykhaeeDepartment of System Biotechnology, National Institute for Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran.
Mohammad Hossein HeydargoyDepartment of Microbiology, College of Basic Sciences, Shahr-e-Qods Branch, Islamic Azad University, Tehran, Iran.
Zahra RafieiDepartment of System Biotechnology, National Institute for Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran.
Gholamreza AhmadianDepartment of System Biotechnology, National Institute for Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The healthcare system has been greatly affected by the COVID-19 pandemic, resulting in an increase in secondary and co-infections among patients. Factors like pulmonary damage and weakened immune systems make patients more susceptible to fungal infections. Mucormycosis, an opportunistic fungal infection, prospers in environments with limited oxygen, and elevated glucose levels due to conditions such as diabetes and steroid use, as well as in acidic environments from metabolic acidosis and diabetic ketoacidosis, where it demonstrates heightened germination ability. Recognizing these complications is critical to minimize harm to patients. The insights gained from this review can improve our understanding of how fungal infections develop in connection to COVID-19, leading to better predictive algorithms, tailored care plans, enhanced antifungal treatments, quicker diagnostics, and improved management strategies.

Indexed as

COVID-19MucormycosisAntifungal AgentsCoinfectionGlobal HealthHumansSARS-CoV-2Antifungal Agentsacidic environment.COVID-19diabetesfungal infectionsimmune suppressionmucormycosis

Identifiers

PMID39484771

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.