Evidence map›Paper›PMID 39484544›Full record

ArticlebioRxiv : the preprint server for biology2024

F-BAR proteins CIP4 and FBP17 function in cortical neuron radial migration and process outgrowth.

Lauren A English, Russell J Taylor, Connor J Cameron, Emily A Broker, Erik W Dent

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Lauren A EnglishNeuroscience Training Program, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53705.ORCID 0009-0005-1342-2012
Russell J TaylorNeuroscience Department, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53705.
Connor J CameronNeuroscience Department, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53705.
Emily A BrokerNeuroscience Department, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53705.
Erik W DentNeuroscience Department, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53705.ORCID 0000-0001-8525-7136

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Christian Capitini · 1985 to 2026
$142.6M
F-BAR proteins in neuronal migration and process formationR01NS115400 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI DENT, ERIK W · 2021 to 2025
$1.9M
NCI NIH HHS P30 CA014520NINDS NIH HHS R01 NS115400
6 · The paper itself

Abstract

Neurite initiation from newly born neurons is a critical step in neuronal differentiation and migration. Neuronal migration in the developing cortex is accompanied by dynamic extension and retraction of neurites as neurons progress through bipolar and multipolar states. However, there is a relative lack of understanding regarding how the dynamic extension and retraction of neurites is regulated during neuronal migration. In recent work we have shown that CIP4, a member of the F-BAR family of membrane bending proteins, inhibits cortical neurite formation in culture, while family member FBP17 induces premature neurite outgrowth. These results beg the question of how CIP4 and FBP17 function in radial neuron migration and differentiation

Identifiers

PMID39484544
PMCPMC11527352

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.