Evidence map›Paper›PMID 39484503›Full record

ArticlebioRxiv : the preprint server for biology2024

An attractor state zone precedes neural crest fate in melanoma initiation.

Alicia M McConnell, Maggie H Chassé, Haley R Noonan, Jeffrey K Mito, Julia Barbano, Erika Weiskopf, Irene F Gosselink, Meera Prasad, Song Yang, Phammela Abarzua and 4 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Alicia M McConnellStem Cell Program and Division of Hematology/Oncology, Children's Hospital Boston, Howard Hughes Medical Institute, Boston, MA 02115, USA.ORCID 0000-0002-0984-4045
Maggie H ChasséStem Cell Program and Division of Hematology/Oncology, Children's Hospital Boston, Howard Hughes Medical Institute, Boston, MA 02115, USA.ORCID 0000-0001-6480-1788
Haley R NoonanStem Cell Program and Division of Hematology/Oncology, Children's Hospital Boston, Howard Hughes Medical Institute, Boston, MA 02115, USA.
Jeffrey K MitoStem Cell Program and Division of Hematology/Oncology, Children's Hospital Boston, Howard Hughes Medical Institute, Boston, MA 02115, USA.
Julia BarbanoStem Cell Program and Division of Hematology/Oncology, Children's Hospital Boston, Howard Hughes Medical Institute, Boston, MA 02115, USA.
Erika WeiskopfStem Cell Program and Division of Hematology/Oncology, Children's Hospital Boston, Howard Hughes Medical Institute, Boston, MA 02115, USA.
Irene F GosselinkStem Cell Program and Division of Hematology/Oncology, Children's Hospital Boston, Howard Hughes Medical Institute, Boston, MA 02115, USA.
Meera PrasadStem Cell Program and Division of Hematology/Oncology, Children's Hospital Boston, Howard Hughes Medical Institute, Boston, MA 02115, USA.
Song YangStem Cell Program and Division of Hematology/Oncology, Children's Hospital Boston, Howard Hughes Medical Institute, Boston, MA 02115, USA.
Phammela AbarzuaProgram in Dermatopathology, Department of Pathology, Brigham and Women's Hospital, Boston, MA 02215, USA.
Christine G LianProgram in Dermatopathology, Department of Pathology, Brigham and Women's Hospital, Boston, MA 02215, USA.
George F MurphyProgram in Dermatopathology, Department of Pathology, Brigham and Women's Hospital, Boston, MA 02215, USA.
Cole TrapnellDepartment of Genome Sciences, University of Washington, Seattle, WA, 98195, USA.
Leonard I ZonStem Cell Program and Division of Hematology/Oncology, Children's Hospital Boston, Howard Hughes Medical Institute, Boston, MA 02115, USA.ORCID 0000-0003-0860-926X

Funding

VectorP30CA006516 · NCI · DANA-FARBER CANCER INSTITUTE · PI Irene M. Ghobrial · 1985 to 2026
$330.6M
Cancer Biology in the ZebrafishR01CA103846 · NCI · CHILDREN'S HOSPITAL BOSTON · PI ZON, LEONARD IRA · 2003 to 2022
$7.5M
Characterizing Chromatin Remodeling Mechanisms of Chemo-Sensitivity and Resistance in Pediatric Solid TumorsK00CA253749 · NCI · BOSTON CHILDREN'S HOSPITAL · PI CHASSE, MAGGIE · 2021 to 2024
$409k
NCI NIH HHS K00 CA253749NCI NIH HHS P30 CA006516NCI NIH HHS R01 CA103846
6 · The paper itself

Abstract

The field cancerization theory suggests that a group of cells containing oncogenic mutations are predisposed to transformation

Identifiers

PMID39484503
PMCPMC11526944

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.