Evidence map›Paper›PMID 39484489›Full record

ArticlebioRxiv : the preprint server for biology2024

Arc mediates intercellular tau transmission via extracellular vesicles.

Mitali Tyagi, Radhika Chadha, Eric de Hoog, Kaelan R Sullivan, Alicia C Walker, Ava Northrop, Balazs Fabian, Monika Fuxreiter, Bradley T Hyman, Jason D Shepherd

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Mitali TyagiDepartment of Neurobiology, University of Utah, Salt Lake City, USA.ORCID 0000-0002-0447-4364
Radhika ChadhaDepartment of Neurobiology, University of Utah, Salt Lake City, USA.
Eric de HoogDepartment of Neurobiology, University of Utah, Salt Lake City, USA.
Kaelan R SullivanDepartment of Neurobiology, University of Utah, Salt Lake City, USA.ORCID 0000-0002-6188-3199
Alicia C WalkerDepartment of Neurobiology, University of Utah, Salt Lake City, USA.ORCID 0009-0000-1511-9037
Ava NorthropDepartment of Neurobiology, University of Utah, Salt Lake City, USA.
Balazs FabianDepartment of Theoretical Biophysics, Max Planck Institute of Biophysics, Germany.
Monika FuxreiterDepartment of Biomedical Sciences University of Padova, Padova, Italy.ORCID 0000-0002-4463-6727
Bradley T HymanDepartment of Neurology, Massachusetts Alzheimer's Disease Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, USA.ORCID 0000-0002-7959-9401
Jason D ShepherdDepartment of Neurobiology, University of Utah, Salt Lake City, USA.ORCID 0000-0001-7384-8289

Funding

Research Education ComponentP30AG062421 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI Christine S Ritchie · 2019 to 2026
$36.5M
Virus-like intercellular communication in the nervous systemR01NS115716 · NINDS · UNIVERSITY OF UTAH · PI CAMPBELL, EDWARD M, GALLAGHER, THOMAS MILLER · 2019 to 2023
$5.3M
LRP1-tau interactions and Alzheimer DiseaseRF1AG073236 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI HYMAN, BRADLEY T., STRICKLAND, DUDLEY K. · 2021 to 2021
$2.4M
LRP1-tau interactions and Alzheimer DiseaseR01AG073236 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI HYMAN, BRADLEY T., STRICKLAND, DUDLEY K. · 2024 to 2025
$1.6M
NIA NIH HHS P30 AG062421NIA NIH HHS R01 AG073236NIA NIH HHS RF1 AG073236NINDS NIH HHS R01 NS115716
6 · The paper itself

Abstract

Intracellular neurofibrillary tangles that consist of misfolded tau protein

Identifiers

PMID39484489
PMCPMC11526995

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.