Evidence map›Paper›PMID 39484462›Full record

ArticlebioRxiv : the preprint server for biology2025

NeuroSC: Exploring Neurodevelopment via Spatiotemporal Collation of Anatomical Networks.

Noelle L Koonce, Sarah E Emerson, Dhananjay Bhaskar, Manik Kuchroo, Mark W Moyle, Pura Arroyo-Morales, Nabor Vázquez Martínez, Jamie I Emerson, Smita Krishnaswamy, William Mohler and 1 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Noelle L KoonceDepartment of Neuroscience and Department of Cell Biology, Wu Tsai Institute, Yale University, New Haven, CT, USA.ORCID 0000-0003-1886-2891
Sarah E EmersonDepartment of Neuroscience and Department of Cell Biology, Wu Tsai Institute, Yale University, New Haven, CT, USA.ORCID 0000-0001-9587-3784
Dhananjay BhaskarDepartment of Genetics, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0001-8068-3101
Manik KuchrooDepartment of Genetics, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0001-7512-9739
Mark W MoyleDepartment of Neuroscience and Department of Cell Biology, Wu Tsai Institute, Yale University, New Haven, CT, USA.
Pura Arroyo-MoralesDepartment of Neuroscience and Department of Cell Biology, Wu Tsai Institute, Yale University, New Haven, CT, USA.ORCID 0000-0001-5369-6097
Nabor Vázquez MartínezDepartment of Neuroscience and Department of Cell Biology, Wu Tsai Institute, Yale University, New Haven, CT, USA.
Jamie I EmersonBilte Co. Ventura, CA, USA.
Smita KrishnaswamyDepartment of Genetics, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0001-5823-1985
William MohlerDepartment of Genetics and Genome Sciences and Center for Cell Analysis and Modeling, University of Connecticut Health Center, Farmington, CT, USA.ORCID 0000-0003-3586-547X
Daniel Colón-RamosDepartment of Neuroscience and Department of Cell Biology, Wu Tsai Institute, Yale University, New Haven, CT, USA.ORCID 0000-0003-0223-7717

Funding

WormGUIDES: A Resource for Global Understanding in Dynamic Embryonic SystemsR24OD016474 · OD · YALE UNIVERSITY · PI BAO, ZHIRONG, COLON-RAMOS, DANIEL A · 2013 to 2020
$6.5M
Powering the Brain: the Cell Biology of NeuroenergeticsDP1NS111778 · NINDS · YALE UNIVERSITY · PI COLON-RAMOS, DANIEL A · 2018 to 2022
$5.9M
Examination of the cell biology of the synapse and behaviorR35NS132156 · NINDS · YALE UNIVERSITY · PI DANIEL A COLON-RAMOS · 2023 to 2026
$4.6M
Cellular and molecular mechanisms that temporally and spatially restrict synapticR01NS076558 · NINDS · YALE UNIVERSITY · PI COLON-RAMOS, DANIEL A · 2012 to 2022
$4.1M
NIH HHS R24 OD016474NINDS NIH HHS DP1 NS111778NINDS NIH HHS R01 NS076558NINDS NIH HHS R35 NS132156
6 · The paper itself

Abstract

Volume electron microscopy (vEM) datasets such as those generated for connectome studies allow nanoscale quantifications and comparisons of the cell biological features underpinning circuit architectures. Quantifying cell biological relationships in the connectome yields rich, multidimensional datasets that benefit from data science approaches, including dimensionality reduction and integrated graphical representations of neuronal relationships. We developed NeuroSC

Identifiers

PMID39484462
PMCPMC11526874

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.